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Electrophysiological evaluation of carpal tunnel syndrome female patients after vitamin D replacement / Avaliação eletrofisiológica de pacientes do sexo feminino com síndrome do túnel do carpo após reposição de vitamina D
Saçmaci, Hikmet; Tanik, Nermin; Balbalou, Özlem; Aktürk, Tülin; Nan, Levent Erturul.
  • Saçmaci, Hikmet; Yozgat Bozok University. Faculty of Medicine. Department of Neurology. Yozgat. TR
  • Tanik, Nermin; Yozgat Bozok University. Faculty of Medicine. Department of Neurology. Yozgat. TR
  • Balbalou, Özlem; Yozgat Bozok University. Faculty of Medicine. Department of Physical Therapy and Rehabilitation. Yozgat. TR
  • Aktürk, Tülin; Yozgat Bozok University. Faculty of Medicine. Department of Neurology. Yozgat. TR
  • Nan, Levent Erturul; Yozgat Bozok University. Faculty of Medicine. Department of Neurology. Yozgat. TR
Arq. neuropsiquiatr ; 78(4): 224-229, Apr. 2020. tab
Article in English | LILACS | ID: biblio-1098085
ABSTRACT
Abstract

Objective:

The effects of vitamin D on the central and peripheral nervous system continue to be investigated today. In the present study, we aimed to evaluate pain and electrophysiologic response in patients with carpal tunnel syndrome (CTS) who have undergone replacement therapy due to vitamin D deficiency.

Methods:

Fifty female patients diagnosed with mild and moderate CTS and accompanied by vitamin D deficiency were included in this study. Nerve conduction study (NCS) was performed before and after vitamin D replacement, and the patient's pain was evaluated with Visual Analogue Scale (VAS).

Results:

When NCS were compared before and after treatment, there was a statistically significant improvement in the median distal sensory onset latency (DSOL) and sensory conduction velocity (CV) and motor distal latencies (DML) values (p=0.001; p<0.001; p=0.001, respectively). At the same time, there was a decrease in the VAS values in patients (p<0.001). When the two groups were compared there was an improvement in DSOL and sensory CV in both groups, but in DML only in moderate CTS group.

Conclusion:

In this study, it was shown that mild and moderate CTS patients had an improvement in pain and electrophysiological parameters after vitamin D replacement. Replacing vitamin D in early stages of CTS may be beneficial.
RESUMO
Resumo

Objetivo:

Os efeitos da vitamina D no sistema nervoso central e periférico continuam sendo investigados atualmente. Neste estudo, objetivamos avaliar a dor e a resposta eletrofisiológica em pacientes com síndrome do túnel do carpo (STC) submetidos a terapia de reposição devido à deficiência de vitamina D.

Métodos:

Cinquenta pacientes do sexo feminino diagnosticadas com STC leve e moderada e acompanhadas de deficiência de vitamina D foram incluídas neste estudo. O estudo da condução nervosa (ECN) foi realizado antes e após a reposição da vitamina D, e a dor do paciente foi avaliada com a Escala Visual Analógica (EVA).

Resultados:

Quando a ECN foi comparada antes e após o tratamento, houve uma melhora estatisticamente significativa na latência mediana do início sensorial distal (DSOL) e nos valores de velocidade de condução sensorial (VC) e latência distal motora (LDM) (p=0,001; p<0,001; p=0,001, respectivamente). Ao mesmo tempo, houve uma diminuição dos valores da EVA nos pacientes (p<0,001). Quando os dois grupos foram comparados, houve uma melhora no DSOL e no VC sensorial em ambos, mas no LDM apenas no grupo STC moderado.

Conclusão:

Neste estudo, foi demonstrado que pacientes com STC leve e moderada apresentaram melhora da dor e parâmetros eletrofisiológicos após a reposição de vitamina D. A substituição da vitamina D nos estágios iniciais da STC pode ser benéfica.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Vitamin D Deficiency / Carpal Tunnel Syndrome Limits: Female / Humans Language: English Journal: Arq. neuropsiquiatr Journal subject: Neurology / Psychiatry Year: 2020 Type: Article Affiliation country: Turkey Institution/Affiliation country: Yozgat Bozok University/TR

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Full text: Available Index: LILACS (Americas) Main subject: Vitamin D Deficiency / Carpal Tunnel Syndrome Limits: Female / Humans Language: English Journal: Arq. neuropsiquiatr Journal subject: Neurology / Psychiatry Year: 2020 Type: Article Affiliation country: Turkey Institution/Affiliation country: Yozgat Bozok University/TR