Your browser doesn't support javascript.
loading
Preliminary analysis of Brazilian Amazonian plant extracts using bench-top assays in a through-put basis aiming the identification of potential antioxidant natural product
Suffredini, Ivana Barbosa; Cavarsan, Ellen Carolina Montagner; Marin, Lucyana Cano; Díaz, Ingrit Elida Collantes; Paciencia, Mateus Luís Barradas; Frana, Sergio Alexandre.
  • Suffredini, Ivana Barbosa; Universidade Paulista. Programa de Pós Graduação em Patologia Ambiental e Experimental. São Paulo. BR
  • Cavarsan, Ellen Carolina Montagner; Universidade Paulista. Programa de Pós Graduação em Patologia Ambiental e Experimental. São Paulo. BR
  • Marin, Lucyana Cano; Universidade Paulista. Programa de Pós Graduação em Patologia Ambiental e Experimental. São Paulo. BR
  • Díaz, Ingrit Elida Collantes; Núcleo de Pesquisas em Biodiversidade da Universidade Paulista. São Paulo. BR
  • Paciencia, Mateus Luís Barradas; Núcleo de Pesquisas em Biodiversidade da Universidade Paulista. São Paulo. BR
  • Frana, Sergio Alexandre; Núcleo de Pesquisas em Biodiversidade da Universidade Paulista. São Paulo. BR
Rev. ciênc. farm. básica apl ; 3801/01/2017. tab, ilus, Graf
Article in English | LILACS | ID: biblio-1100220
ABSTRACT
Plants are a source of compounds that are used for the treatment of human and veterinary diseases. Brazil is one of the richest countries in the world in terms of biodiversity. The present study evaluated extracts using thin-layer chromatography to identify antioxidant activity and determine the presence of groups of compounds, in a large-scale basis. A total of 1,260 aqueous and organic extracts were obtained from plants that were collected in the Amazon and Atlantic rain forests. Thin-layer chromatography was performed to evaluate the presence of alkaloids, anthraquinones, cardioactive glicosides, terpenes, and phenolics and determine antioxidant and radical scavenging activity using the following reagents Dragendorff's reagent, KOH, Kedde's reagent, sulphuric acid, NP reagent, ß-carotene, and 2,2-diphenyl-1-picrylhydrazyl (DPPH). Of the 1,260 extracts, 837 (66.43%) presented a ß-carotene/bleaching response, and 1,205 (95.63%) presented a radical scavenging response. Alkaloids were found in 203 extracts (16.11%). Anthraquinones were found in 14 extracts (1.11%), cardenolides were found in eight extracts (0.63%). The present findings shows the importance of the Brazilian Amazon plants as sources of antioxidant and radical scavenging active compounds.(AU)
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Plant Extracts / Amazonian Ecosystem / Annonaceae / Antioxidants Type of study: Diagnostic study / Prognostic study Country/Region as subject: South America / Brazil Language: English Journal: Rev. ciênc. farm. básica apl Journal subject: Pharmacology Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Núcleo de Pesquisas em Biodiversidade da Universidade Paulista/BR / Universidade Paulista/BR

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: LILACS (Americas) Main subject: Plant Extracts / Amazonian Ecosystem / Annonaceae / Antioxidants Type of study: Diagnostic study / Prognostic study Country/Region as subject: South America / Brazil Language: English Journal: Rev. ciênc. farm. básica apl Journal subject: Pharmacology Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Núcleo de Pesquisas em Biodiversidade da Universidade Paulista/BR / Universidade Paulista/BR