Multicenter study of Candida species in oral mucosa of different patients: analysis of 711 strains and literature review
Rev. patol. trop
;
49(2): 105-119, 2020. ilus, tab, graf
Article
in English
| LILACS
| ID: biblio-1118279
ABSTRACT
This study aimed to identify Candida spp. collected from oral mucosa and maintained in culture collections, correlating the findings with the medical history of patients and comparing with data from the literature over the past five years. Seven hundred and eleven oral Candida spp. isolates, collected between 2013 and 2017, were selected and identified using traditional and molecular methods. In addition, a literature review was performed with the key words "Oral", "Candida" and "Yeast". Seven species of the genus Candida were identified C. albicans(73.3%); C. tropicalis (9.3%); C. parapsilosis (8.2%); C. glabrata (3.9%); C. guilliermondii(2.8%); C. krusei (1.7%) and C. lusitaniae (0.3%). The strains identified as C. albicans were submitted to molecular methods using specific primers and of these, 5.8% were identified as C. dubliniensis strains. The greatest diversity of strains was found in patients presenting no systemic diseases or HIV +, while the highest percentage of strains of Candidanon-albicanswere observed in cancer patients. This study reports a representative distribution of Candidaspecies among individuals exhibiting distinct clinical conditions, in order to contribute to the design of future research on details of aspects involved in the infections caused by these microorganisms. The correct identification of oral Candida strains contributes to a realistic epidemiological approach and future clinical protocols against these pathogens
Full text:
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Index:
LILACS (Americas)
Main subject:
Candida
/
HIV
/
Mouth Mucosa
/
Neoplasms
Type of study:
Controlled clinical trial
/
Practice guideline
/
Prognostic study
Language:
English
Journal:
Rev. patol. trop
Journal subject:
Tropical Medicine
/
Pathology
Year:
2020
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Adolfo Lutz Institute/BR
/
Instituto Adolfo Lutz/BR
/
Universidade de Alfenas/BR
/
Universidade de São Paulo/BR
/
Universidade de Unicentro/BR
/
University of São Paulo/BR
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