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Impairment of myocardial functions and arterial stiffness in patients with lichen planus
Baykal Selcuk, Leyla; Sahin, Mursel; Arıca, Deniz Aksu; Orem, Asım; Karaca Ural, Zeynep; Yaylı, Savaş.
  • Baykal Selcuk, Leyla; Karadeniz Technical University. School of Medicine. Department of Dermatology. Trabzon. TR
  • Sahin, Mursel; Karadeniz Technical University. School of Medicine. Department of Dermatology. Trabzon. TR
  • Arıca, Deniz Aksu; Karadeniz Technical University. School of Medicine. Department of Dermatology. Trabzon. TR
  • Orem, Asım; Karadeniz Technical University. School of Medicine. Department of Biochemistry. Trabzon. TR
  • Karaca Ural, Zeynep; Karadeniz Technical University. School of Medicine. Department of Dermatology. Trabzon. TR
  • Yaylı, Savaş; Karadeniz Technical University. School of Medicine. Department of Dermatology. Trabzon. TR
An. bras. dermatol ; 95(2): 180-186, Mar.-Apr. 2020. tab, graf
Article in English | LILACS, ColecionaSUS | ID: biblio-1130838
ABSTRACT
Abstract

Background:

Lichen planus is a chronic inflammatory mucocutaneous disease. Recent studies have suggested that it is associated with an increased risk of cardiovascular comorbidities.

Objective:

The purpose of this study was to assess and compare arterial stiffness and cardiovascular hemodynamics in patients with lichen planus and a healthy control group.

Methods:

Fifty-five patients with lichen planus and 42 healthy controls were enrolled. All patients underwent echocardiographic examination, and arterial stiffness was measured using applanation tonometry.

Results:

No statistically significant difference was determined between the patient and control groups in terms of arterial stiffness, but stiffness was markedly higher in patients with erosive lichen planus compared to the control group and other patients (p = 0.006, and p = 0.023, respectively). Moderate positive correlation was determined between duration of disease and arterial stiffness. Impairment of systolic and diastolic functions was also determined in patients with lichen planus compared to the control group (p < 0.001, and p = 0.005, respectively). Study

limitations:

Relatively low number of patients.

Conclusion:

The positive correlation observed between duration of disease and arterial stiffness in patients with lichen planus suggests that these patients should be followed-up in terms of cardiovascular risk in the presence of resistant and long-term disease, particularly in case of erosive lichen planus.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Cardiovascular Diseases / Vascular Stiffness / Hemodynamics / Lichen Planus Type of study: Etiology study / Observational study / Prognostic study / Risk factors Limits: Adult / Female / Humans / Male Language: English Journal: An. bras. dermatol Year: 2020 Type: Article Institution/Affiliation country: Karadeniz Technical University/TR

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Full text: Available Index: LILACS (Americas) Main subject: Cardiovascular Diseases / Vascular Stiffness / Hemodynamics / Lichen Planus Type of study: Etiology study / Observational study / Prognostic study / Risk factors Limits: Adult / Female / Humans / Male Language: English Journal: An. bras. dermatol Year: 2020 Type: Article Institution/Affiliation country: Karadeniz Technical University/TR