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Signet ring cells in carcinomatous lymphangitis due to gastric adenocarcinoma,
Souza, Beatriz da Silva; Bonamigo, Renan Rangel; Viapiana, Gabriela Lusa; Cartell, André.
  • Souza, Beatriz da Silva; Hospital de Clínicas de Porto Alegre. Dermatology Service. Porto Alegre. BR
  • Bonamigo, Renan Rangel; Hospital de Clínicas de Porto Alegre. Dermatology Service. Porto Alegre. BR
  • Viapiana, Gabriela Lusa; Hospital de Clínicas de Porto Alegre. Dermatology Service. Porto Alegre. BR
  • Cartell, André; Universidade Federal do Rio Grande do Sul. Faculdade de Medicina. Department of Pathology. Porto Alegre. BR
An. bras. dermatol ; 95(4): 490-492, July-Aug. 2020. graf
Article in English | LILACS-Express | LILACS, ColecionaSUS | ID: biblio-1130927
Responsible library: BR1.1
ABSTRACT
Abstract Cutaneous metastases are rare. They usually present as nodules or tumors. Diagnosis is based on histopathological examination and prognosis is unfavorable. This report describes the case of a female patient, 72 years old, with surgically treated gastric antrum adenocarcinoma. Pathology showed poorly differentiated adenocarcinoma with signet ring cells. It evolved with bone involvement, lymph node enlargement in the inguinal region, and skin infiltration in the lower limbs, abdomen, and root of the upper limbs. Skin biopsy demonstrated signet ring carcinoma embolizing the dermal and hypodermic vessels and invasion of adipose tissue, confirming carcinomatous lymphangitis. Carcinomatous lymphangitis is the cutaneous and subcutaneous lymphatic invasion by tumor cells. Cutaneous metastasis is relatively uncommon and presents mainly as cutaneous or subcutaneous nodules, and more rarely as inflammatory lesions. The present case reports carcinomatous lymphangitis associated with gastric cancer.


Full text: Available Index: LILACS (Americas) Language: English Journal: An. bras. dermatol Year: 2020 Type: Article Institution/Affiliation country: Hospital de Clínicas de Porto Alegre/BR / Universidade Federal do Rio Grande do Sul/BR

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Full text: Available Index: LILACS (Americas) Language: English Journal: An. bras. dermatol Year: 2020 Type: Article Institution/Affiliation country: Hospital de Clínicas de Porto Alegre/BR / Universidade Federal do Rio Grande do Sul/BR