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The effects of propofol and midazolam on rat spermatogenic parameters / [Efeitos do propofol e midazolam em parâmetros espermatogênicos em ratos]
Celaleddin, S; Volkan, K.
  • Celaleddin, S; Yuzuncu Yil University. School of Medicine. Department of Anaesthesiology and Reanimation. Van. TR
  • Volkan, K; Van Yuzuncu Yil University. Veterinary Faculty. Department of Artificial Insemination. Van. TR
Arq. bras. med. vet. zootec. (Online) ; 72(5): 1727-1730, Sept.-Oct. 2020. tab
Article in English | LILACS, VETINDEX | ID: biblio-1131576
ABSTRACT
There is a need for various anesthetic agents to obtain sperm in the field of human and veterinary medicine. Propofol and midazolam are among the most preferred among these agents. The aim of this study was to determine how sperm paramaters are affected according to the anesthetic agent used. Propofol (2mg/kg) and midazolam (3,5-7,5mg/kg) were administered twice a day (morning-evening) for one week. As a result of this study, there was no statistical difference in sperm density and abnormal sperm rates (respectively P=0,673, P=0,479). Sperm motility rates are similar in the control and propofol groups, while the motility rate in the midazolam group is statistically lower. (Control group %85 - Midazolam group %68.75 - Propofol group %83.75), (P<0.05). As a result of this study, the confidence interval of propofol was higher than the other anesthetic agents used for sperm retrieval.(AU)
RESUMO
São necessários vários agentes anestésicos para obter espermatozoides no campo da medicina humana e veterinária. Propofol e midazolam estão entre os agentes preferidos. O objetivo deste estudo foi determinar como os parâmetros de esperma são afetados de acordo com o agente anestésico utilizado. Propofol (2mg / kg) e midazolam (3,5-7,5mg / kg) foram administrados duas vezes ao dia (manhã e noite) durante uma semana. Neste estudo, não houve diferença estatística na densidade espermática e nas taxas anormais de espermatozoides (respectivamente P = 0,673, P = 0,479). As taxas de motilidade espermática são semelhantes nos grupos controle e propofol, enquanto a taxa de motilidade no grupo midazolam é estatisticamente menor. (Grupo controle % 85 - grupo midazolam % 68,75 - grupo propofol % 83,75), (P <0,05). Neste estudo, o intervalo de confiança do propofol foi maior do que os outros agentes anestésicos utilizados na recuperação espermática.(AU)
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Semen / Spermatozoa / Midazolam / Propofol Limits: Animals Language: English Journal: Arq. bras. med. vet. zootec. (Online) Year: 2020 Type: Article Institution/Affiliation country: Van Yuzuncu Yil University/TR / Yuzuncu Yil University/TR

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Full text: Available Index: LILACS (Americas) Main subject: Semen / Spermatozoa / Midazolam / Propofol Limits: Animals Language: English Journal: Arq. bras. med. vet. zootec. (Online) Year: 2020 Type: Article Institution/Affiliation country: Van Yuzuncu Yil University/TR / Yuzuncu Yil University/TR