Unusual abscess masquerading as poorly differentiated adenocarcinoma of the colon showing characteristics of choriocarcinoma
Autops. Case Rep
;
10(3): e2020145, 2020. tab, graf
Article
in English
| LILACS
| ID: biblio-1131836
ABSTRACT
Extragonadal non-gestational choriocarcinoma (ENC) is an uncommon malignant tumor occasionally found in the gastrointestinal tract. ENC is characterized by a biphasic tumor growth with distinct areas of adenocarcinoma and choriocarcinoma differentiation. Primary choriocarcinoma of the colon is extremely rare, with only 21 cases reported in the literature. Most of the perforation of colorectal cancers occurs in the abdominal cavity, while abdominal wall abscess is rare; the psoas abscess associated with colon carcinoma is even less observed. Herein, we report the case of a 61-year-old female with poorly differentiated adenocarcinoma of the ascending colon and sigmoid, with choriocarcinomatous differentiation, masquerading a psoas abscess formation. Unfortunately, despite the aggressive therapy, the patient's disease rapidly progressed, and she died within 2 months after the diagnosis. The typical morphological pattern, immunohistochemistry, and its correlation with serum β-human chorionic gonadotropin enabled a correct diagnosis.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Colorectal Neoplasms
/
Adenocarcinoma
/
Psoas Abscess
/
Colon
/
Choriocarcinoma, Non-gestational
Type of study:
Diagnostic study
Limits:
Female
/
Humans
Language:
English
Journal:
Autops. Case Rep
Journal subject:
Anatomia
/
Patologia Cl¡nica
/
Patologia Legal
Year:
2020
Type:
Article
Affiliation country:
Greece
Institution/Affiliation country:
Ippokratio Hospital/GR
/
National and Kapodistrian University of Athens/GR
/
University of Ioannina School of Health Sciences/GR
/
University of Ioannina/GR
/
University of Ioannina, School of Health Sciences/GR
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