Childhood-maltreatment subtypes in bipolar patients with suicidal behavior: systematic review and meta-analysis
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
;
42(5): 558-567, Sept.-Oct. 2020. tab, graf
Article
in English
| LILACS
| ID: biblio-1132124
ABSTRACT
Objective:
Patients with bipolar disorders have a high risk of suicidal behavior. Childhood maltreatment is a well-established risk factor for suicidal behavior. The objective of this study was to examine the association between childhood-maltreatment subtypes and vulnerability to suicide attempts in bipolar disorder using the Childhood Trauma Questionnaire (CTQ).Methods:
A literature review was performed using the MEDLINE, Embase, and PsycINFO databases. Thirteen studies met the selection criteria. In the meta-analysis, the Childhood Trauma Questionnaire (CTQ) was used to assess a wide range of childhood maltreatment subtypes, which were analyzed by using a random-effects model to account for the likely variations of true effect sizes between the included studies.Results:
In the systematic review, 13 studies met the selection criteria. The CTQ was selected for the meta-analysis to increase the homogeneity of assessment and to encompass a wide range of childhood-maltreatment subtypes. The data were analyzed using a random-effects model. Compared to bipolar non-attempters, bipolar suicide attempters had experienced childhood maltreatment with a significantly higher frequency and had higher total CTQ scores (Hedges' g = -0.38, 95%CI -0.52 to -0.24, z = -5.27, p < 0.001) and CTQ sub-scores (sexual abuse g = -0.39, 95%CI -0.52 to -0.26, z = -5.97; physical abuse g = -0.26, 95%CI -0.39 to -0.13, z = -4.00; emotional abuse g = -0.39, 95%CI -0.65 to -0.13, z = -2.97; physical neglect g = -0.18, 95%CI -0.31 to -0.05, z = -2.79; emotional neglect g = -0.27, 95%CI -0.43 to -0.11, z = -3.32).Conclusions:
Childhood maltreatment, as assessed by the CTQ, may contribute to an increased risk of suicidal behavior among people with bipolar disorders. Recognizing maltreatment as an etiological risk factor is a crucial step toward furthering science-based preventive psychiatry.
Full text:
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Index:
LILACS (Americas)
Main subject:
Bipolar Disorder
/
Child Abuse
/
Adult Survivors of Child Abuse
Type of study:
Prognostic study
/
Risk factors
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Systematic reviews
Limits:
Child
/
Humans
Language:
English
Journal:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Journal subject:
Psychiatry
Year:
2020
Type:
Article
Affiliation country:
Brazil
/
Canada
/
France
Institution/Affiliation country:
Groupe Hospitalo-Universitaire (G.H.U.) Saint Louis-Lariboisiere-Fernand-Widal, Université Paris Diderot/FR
/
McGill Group for Suicide Studies, Department of Psychiatry, Douglas Mental Health University Institute, McGill University/CA
/
Universidade Federal de Minas Gerais/BR
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