Anatomical, Histochemical and Biological Studies of Clusia grandiflora Splitg. (Clusiaceae)
Braz. arch. biol. technol
;
63: e20190674, 2020. tab, graf
Article
in English
| LILACS
| ID: biblio-1132236
ABSTRACT
Abstract Clusia grandiflora belongs to an important botanical family which is known for its medicinal value, however there are few reports in literature about the species, highlighting the relevance of this study. Anatomical studies with leaves and stems were performed using traditional techniques. In this investigation it was identified particularities of the species such as the presence of vascular system arranged in an opened arc-shaped with the flexed ends towards the inside of the arch with accessory bundles in the petiole. In histochemical studies, performed with different reagents, alkaloids, phenols substances, carbohydrates and lipids were located. The cytotoxic activity of the extracts was performed by tetrazole salt and showed promising results for ethanolic extracts of stems (IC50 human colon cells of 24.30 μg/ mL) and leaves (IC50 ascites gastric cells of 44.15 μg/ mL), without cell membrane disruption of erythrocytes. The antibacterial activity was evaluated by tryptic soy agar and minimal inhibitory concentration assays and showed positive results for Pseudomonas aeruginosa and Escherichia coli, with better result for adventitious roots (32 μg/ mL and 16 μg/ mL, respectively), stems (64 μg/ mL and 32 μg/ mL, respectively) and leaves (64 μg/ mL and 32 μg/ mL, respectively) ethanolic extracts. Thus, these studies were able to characterize the species and show its potential as promising source of active substances.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Plant Extracts
/
Clusia
/
Gram-Negative Bacteria
/
Gram-Positive Bacteria
/
Anti-Bacterial Agents
Language:
English
Journal:
Braz. arch. biol. technol
Journal subject:
Biology
Year:
2020
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Botanical Garden of Rio de Janeiro Research Institute/BR
/
Federal University of Ceará/BR
/
Federal University of Pará/BR
/
Fluminense Federal University/BR
Similar
MEDLINE
...
LILACS
LIS