Restless Legs Syndrome, and symptoms of Restless Syndrome in patients with Graves disease: a cross-sectional survey
Clinics
;
75: e2140, 2020. tab
Article
in English
| LILACS
| ID: biblio-1133426
ABSTRACT
OBJECTIVES:
Restless legs syndrome (RLS) is a frequent comorbid condition associated with distinct unrelated diseases. While the incidence of RLS has not been definitively confirmed, RLS-like symptoms have been reported in a section of Asian population who also had hyperthyroidism. The prevalence of RLS is generally low in Asian populations. Under these circumstances, we hypothesized that in a population where RLS is common, such as in Brazil, RLS could manifest as a comorbid ailment alongside Graves' disease, a common hyperthyroid condition.METHODS:
In a cross-sectional survey, 108 patients who presented with Graves' disease were analyzed for restless legs or associated symptoms.RESULTS:
Twelve patients (11.1%) displayed symptoms of RLS prior to the incidence of Graves' disease. These patients experienced worsening of the symptoms during their hyperthyroid state. Six patients (5.6%) developed RLS, consequent upon the incidence of Graves' disease as per the consensus of the panel of the experts. Fifteen patients (13.9%) also presented with RLS-like symptoms without any discernible circadian feature of the syndrome.CONCLUSION:
Our findings confirm that Graves' disease might trigger restless legs-like symptoms, while the condition of hyperthyroidism could also be complicated by definite RLS.
Full text:
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Index:
LILACS (Americas)
Main subject:
Restless Legs Syndrome
/
Graves Disease
Type of study:
Diagnostic study
/
Observational study
/
Prevalence study
/
Risk factors
Limits:
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Clinics
Journal subject:
Medicine
Year:
2020
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Departamento de Pediatria/BR
/
Universidade Federal Paulista/BR
/
Universidade Federal de Sao Paulo/BR
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