Multidisciplinary diagnostics of chronic lymphocytic leukemia: European Research Initiative on CLL - ERIC recommendations
Hematol., Transfus. Cell Ther. (Impr.)
;
42(3): 269-274, July-Sept. 2020. ilus
Article
in English
| LILACS
| ID: biblio-1134046
ABSTRACT
ABSTRACT Recent advances in chronic lymphocytic leukemia (CLL) includes description of disease genomic landscape, inclusion of prognostic relevant genetic tests in CLL workflow and evaluation of minimal residual disease (MRD)1 in parallel with the increase availability of novel therapy agents.In this review, the theoretical and practical aspects of response assessment have been discussed. These are based on updated recommendations of the European Research Initiative on Chronic Lymphocytic Leukemia (ERIC) for genetic tests (TP53 mutation and IGHV status) and flow cytometry analysis for CLL. Methodological approaches and interpretation of results were also discussed.2,3
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Leukemia, Lymphocytic, Chronic, B-Cell
/
Genes, p53
/
Neoplasm, Residual
/
Flow Cytometry
/
Mutation
Type of study:
Diagnostic study
/
Practice guideline
/
Prognostic study
Language:
English
Journal:
Hematol., Transfus. Cell Ther. (Impr.)
Journal subject:
Hematologia
/
TransfusÆo de Sangue
Year:
2020
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Diagnósticos da América/BR
/
GeneOne/BR
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