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Low risk of serological cross-reactivity between dengue and COVID-19
Spinicci, Michele; Bartoloni, Alessandro; Mantella, Antonia; Zammarchi, Lorenzo; Rossolini, Gian Maria; Antonelli, Alberto.
  • Spinicci, Michele; University of Florence. Department of Experimental and Clinical Medicine. Florence. IT
  • Bartoloni, Alessandro; University of Florence. Department of Experimental and Clinical Medicine. Florence. IT
  • Mantella, Antonia; University of Florence. Department of Experimental and Clinical Medicine. Florence. IT
  • Zammarchi, Lorenzo; University of Florence. Department of Experimental and Clinical Medicine. Florence. IT
  • Rossolini, Gian Maria; University of Florence. Department of Experimental and Clinical Medicine. Florence. IT
  • Antonelli, Alberto; University of Florence. Department of Experimental and Clinical Medicine. Florence. IT
Mem. Inst. Oswaldo Cruz ; 115: e200225, 2020.
Article in English | LILACS, SES-SP | ID: biblio-1135239
ABSTRACT
In the near future, the overlap of Coronavirus disease 2019 (COVID-19) and dengue epidemics is a concrete threat in tropical regions. Co-epidemics of COVID-19 and dengue could be an overwhelming challenge for health systems in low- and middle-income countries. In this work, we investigated potential serological cross-reactions between COVID-19 and dengue patients. Among 32 COVID-19 positive sera, no positive Dengue virus (DENV) IgG/IgM results were observed. On the other hand, one false-positive result was observed among 44 DENV-positive sera tested for COVID-19 antibodies with each of the two rapid tests used. Further data on accuracy of COVID-19 diagnostic test are urgently warranted.
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Full text: Available Index: LILACS (Americas) Main subject: Pneumonia, Viral / Coronavirus Infections / Cross Reactions / Dengue / Antibodies, Viral Type of study: Etiology study / Risk factors Limits: Humans Language: English Journal: Mem. Inst. Oswaldo Cruz Year: 2020 Type: Article Institution/Affiliation country: University of Florence/IT

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Full text: Available Index: LILACS (Americas) Main subject: Pneumonia, Viral / Coronavirus Infections / Cross Reactions / Dengue / Antibodies, Viral Type of study: Etiology study / Risk factors Limits: Humans Language: English Journal: Mem. Inst. Oswaldo Cruz Year: 2020 Type: Article Institution/Affiliation country: University of Florence/IT