Abdominal angiostrongyliasis can be diagnosed with a immunochromatographic rapid test with recombinant galactin from Angiostrongylus cantonensis
Mem. Inst. Oswaldo Cruz
;
115: e200201, 2020. tab
Article
in English
| LILACS, SES-SP
| ID: biblio-1135281
ABSTRACT
Angiostrongylus costaricensis is the causative agent of abdominal angiostrongyliasis, a zoonotic infection that may produce severe eosinophilic enterocolitis or hepatitis in humans. Parasites are usually not released in stools and serology has an important role in diagnosis. Since cross-reactivity is demonstrated between A. costaricensis and another metastrongylid worm, A. cantonensis, we tested heterologous recombinant galectin as a probe in an immunochromatographic rapid diagnostic test (ICT-RDT) for detection of anti-A. costaricensis antibodies. Almost all (11/12) positive control sera from A. costaricensis infected patients were positive at ICT RDT. These are preliminary indications that r-galectin ICT-RDT is useful for diagnosing A. costaricensis infection.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Strongylida Infections
/
Angiostrongylus cantonensis
/
Angiostrongylus
Type of study:
Diagnostic study
Limits:
Animals
/
Humans
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Year:
2020
Type:
Article
Institution/Affiliation country:
Instituto de Patologia/BR
/
Khon Kaen University/TH
/
Pontifícia Universidade Católica do Rio Grande do Sul/BR
/
Universidade do Espírito Santo/BR
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