Protein Profiles of Individuals with Erosive Tooth Wear
Pesqui. bras. odontopediatria clín. integr
;
20: e0026, 2020. tab
Article
in English
| LILACS, BBO
| ID: biblio-1135483
ABSTRACT
Abstract Objective:
To determine if protein profiles identified in saliva could be used to determine risk and severity of erosive tooth wear. Material andMethods:
Three types of saliva sampling were performed to obtain saliva from 34 18-year old individuals that received regular dental check-ups, along with clinical status of the dentition and risk factor related to erosive tooth wear using the VEDE scale. Protein profiles in saliva were determined using electrophoresis and the calculation of the percentage of a specific band at a specific molecular weight in relationship to the total protein in that sample (% of total) using molecular weight standards. This quantification was repeated for each protein band across a range of molecular weights for each sample to test for association with erosive tooth wear status.Results:
There were no differences in the number of detectable proteins sourced from the parotid gland, nor the unstimulated and stimulated whole saliva. Five out of the 34 individuals had no signs of erosive tooth wear despite an acidic diet and were more likely to have proteins with molecular weight smaller than 1 KDa (p=0.03).Conclusion:
There is potential for the use of protein profiling to determine risks for erosive tooth wear.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Tooth Erosion
/
Risk Factors
/
Dental Caries
/
Dental Enamel
/
Tooth Wear
Type of study:
Etiology study
/
Practice guideline
/
Prognostic study
/
Risk factors
Limits:
Adolescent
/
Female
/
Humans
/
Male
Country/Region as subject:
Europa
Language:
English
Journal:
Pesqui. bras. odontopediatria clín. integr
Journal subject:
Dentistry
Year:
2020
Type:
Article
Affiliation country:
United States
Institution/Affiliation country:
University of Arizona/US
/
University of Pittsburgh/US
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