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Assessment of the hemogram parameters in patients with paroxysmal supraventricular tachycardia: a retrospective study
Cosgun, Mehmet; Gunes, Yilmaz; Sincer, Isa; Mansiroglu, Asli Kurtar.
  • Cosgun, Mehmet; Bolu Abant Izzet Baysal University. Department of Cardiology. Bolu. TR
  • Gunes, Yilmaz; Bolu Abant Izzet Baysal University. Department of Cardiology. Bolu. TR
  • Sincer, Isa; Bolu Abant Izzet Baysal University. Department of Cardiology. Bolu. TR
  • Mansiroglu, Asli Kurtar; Bolu Abant Izzet Baysal University. Department of Cardiology. Bolu. TR
Rev. Assoc. Med. Bras. (1992) ; 66(10): 1371-1375, Oct. 2020. tab, graf
Article in English | SES-SP, LILACS | ID: biblio-1136164
ABSTRACT
SUMMARY

OBJECTIVE:

Inflammation has been suggested as a potential mechanism in the pathogenesis of arrhythmia. Hemogram parameters such as monocyte count to high-density lipoprotein cholesterol ratio (MHR), neutrophil/lymphocyte ratio (NLR), and monocyte/lymphocyte ratio (MLR) have been considered to be markers of inflammation and new cardiovascular risk predictors. This retrospective study aimed to investigate the relationship between MHR, NLR, and MLR in patients with paroxysmal supraventricular tachycardia (PSVT).

METHODS:

A retrospective study conducted at a university hospital in Bolu, Turkey, between 2017 and 2019. Our study included 196 patients who underwent electrophysiological study (EPS) due to palpitation or documented PSVT on electrocardiography (ECG). Patients having documented atrioventricular nodal re-entrant tachycardia (AVNRT) on ECG or inducible AVNRT on EPS were included in the PSVT group (n=130), and patients with palpitation but without inducible arrhythmia on EPS (n=66) were included in the control group. Routine biochemical and hemogram tests were performed before the EPS procedure.

RESULTS:

When hemogram parameters were compared, there was no statistically significant difference in MHR values [0.010 (0.001-0.030) vs 0.010 (0.001-0.020) p =0.67]. Additionally, both NLR [2.21(0.74-11.36) vs 1.98(0.72-24.87) p=0.13] and MLR [0.25 (0.03-1.05) vs 0.24(0.07-1.39) p=0.41] were not statistically significant between the two groups.

CONCLUSION:

There is no significant difference in PSVT patients regarding hemogram parameters including white blood cell subtypes, MLR, NLR, and MHR. Therefore the evaluation of hemogram parameters may not be clinically relevant for PSVT patients.
RESUMO
RESUMO

OBJETIVO:

A inflamação tem sido sugerida como um mecanismo potencial na patogênese da arritmia. Parâmetros do hemograma, como contagem de monócitos e razão de colesterol lipoproteína de alta densidade (MHP), proporção de neutrófilos / linfócitos (NLP) e proporção de monócitos / linfócitos (MLR), foram considerados marcadores de inflamação e novos preditores de risco cardiovascular. Este estudo retrospectivo teve como objetivo investigar a relação entre MHP, NLP e MLP em pacientes com taquicardia paroxística supraventricular (PSVT).

MÉTODOS:

Estudo retrospectivo realizado em um hospital universitário em Bolu, Turquia, entre 2017 e 2019. Nosso estudo incluiu 196 pacientes submetidos a estudo eletrofisiológico (EPS) devido a palpitações ou PSVT documentada na eletrocardiografia (ECG). Os pacientes com taquicardia nodal atrioventricular reentrante (AVNRT) no ECG ou AVNRT indutível no EPS foram incluídos no grupo PSVT (n = 130) e os pacientes com palpitações sem arritmia induzível no EPS (n = 66) foram incluídos no grupo controle. Testes bioquímicos e de hemograma de rotina foram realizados antes do procedimento de EPS.

RESULTADOS:

Quando os parâmetros do hemograma foram comparados, não houve diferença estatisticamente significante nos valores de MHP (0,010 (0,001-0,030) vs 0,010 (0,001-0,020) p = 0,67). Além disso, tanto o NLP (2,21 (0,74-11,36) vs 1,98 (0,72-24,87) p = 0,13) quanto o MLP (0,25 (0,03-1,05) vs 0,24 (0,07-1,39) p = 0,41) não foram estatisticamente significantes entre os dois grupos.

CONCLUSÃO:

Não há diferença significativa nos pacientes com PSVT em relação aos parâmetros do hemograma, incluindo os subtipos de glóbulos brancos, MHP, NLP e MHP. Portanto, a avaliação dos parâmetros do hemograma pode não ser clinicamente relevante para pacientes com PSVT.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Tachycardia, Paroxysmal / Tachycardia, Supraventricular / Tachycardia, Ventricular Type of study: Observational study / Prognostic study / Risk factors Country/Region as subject: Asia Language: English Journal: Rev. Assoc. Med. Bras. (1992) Year: 2020 Type: Article Institution/Affiliation country: Bolu Abant Izzet Baysal University/TR

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Full text: Available Index: LILACS (Americas) Main subject: Tachycardia, Paroxysmal / Tachycardia, Supraventricular / Tachycardia, Ventricular Type of study: Observational study / Prognostic study / Risk factors Country/Region as subject: Asia Language: English Journal: Rev. Assoc. Med. Bras. (1992) Year: 2020 Type: Article Institution/Affiliation country: Bolu Abant Izzet Baysal University/TR