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Serum ferritin levels is associated with acute myocardial infarction: a meta-analysis
Wen, Shuang; Yang, Liu; He, Lianping; Liu, Changwei.
Affiliation
  • Wen, Shuang; Nanjing Medical University. Department of Immunology. Nanjing. CN
  • Yang, Liu; Nanjing Medical University. Department of Immunology. Nanjing. CN
  • He, Lianping; Anhui Polytechnic University. College of Experience Industry. Wuhu. CN
  • Liu, Changwei; Nanjing Medical University. Childrens Hospital. Nanjing. CN
Rev. Assoc. Med. Bras. (1992, Impr.) ; Rev. Assoc. Med. Bras. (1992, Impr.);66(2): 227-231, Feb. 2020. tab, graf
Article in En | SES-SP, LILACS | ID: biblio-1136169
Responsible library: BR1.1
ABSTRACT
SUMMARY BACKGROUND An association between increased serum ferritin levels and acute myocardial infarction (AMI) remains controversial. The purpose of this meta-analysis is to confirm the association between increased serum ferritin levels and AMI. METHODS We searched PubMed and China National Knowledge Infrastructure (CNKI) for relevant articles that assessed the association between serum ferritin and acute myocardial infarction using terms that included serum ferritin and acute myocardial infarction up to February 13, 2019. RESULTS A total of 11 studies were identified for analysis. All pooled analysis was based on a random-effects models. The variance was exhibited using a forest plot, and the heterogeneity among studies was examined using the I2 index, the publication bias was evaluated using a funnel plot. The pooled standard mean difference of ferritin levels between AMI and controls was 0.78 (95%CI,0.68-0.88). CONCLUSION The results of this meta-analysis demonstrate that serum ferritin in acute myocardial infarction patients is higher than that of healthy controls.
RESUMO
RESUMO ANTECEDENTES a correlação entre o aumento do nível de proteínas de ferro no soro e o infarto agudo do miocárdio (AMI) continua controversa. O objetivo desta análise é confirmar a relação entre o aumento dos níveis de proteínas de ferro no soro y o AMI. METODOLOGIA busca de artigos sobre Pubmed e a infraestrutura nacional de conhecimentos da China (cnki) para avaliar a relação entre a proteína de ferro no soro e o infarto agudo do miocárdio, incluída a proteína de ferro no soro e o infarto agudo de miocárdio, até 13 de fevereiro de 2019. RESULTADO foram identificados 11 estudos para sua analise e todas as análises resumidas tiveram base em modelos de efeitos aleatórios. Foram utilizados mapas florestais para mostrar as margens, foi utilizado o índice 12 para examinar a heterogeneidade dos estudos e foram utilizados mapas de funil para avaliar os desvios publicados.A diferença entre a norma de fusão dos níveis de proteína de ferro do Grupo ami e o Grupo de controle é de 0,78 (intervalo de confiança de 95% 0,68-0,88). CONCLUSÃO nos resultados das análises da meta indicam que os pacientes com infarto agudo do miocárdio têm proteínas de ferro superiores às do Grupo de controle de saúde.
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Full text: 1 Index: LILACS Main subject: Ferritins / Myocardial Infarction Type of study: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: Rev. Assoc. Med. Bras. (1992, Impr.) Journal subject: Educa‡Æo em Sa£de / GestÆo do Conhecimento para a Pesquisa em Sa£de / MEDICINA Year: 2020 Type: Article

Full text: 1 Index: LILACS Main subject: Ferritins / Myocardial Infarction Type of study: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: Rev. Assoc. Med. Bras. (1992, Impr.) Journal subject: Educa‡Æo em Sa£de / GestÆo do Conhecimento para a Pesquisa em Sa£de / MEDICINA Year: 2020 Type: Article