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Association between atherogenic dyslipidemia and fourniers gangrene
Akan, Serkan; Urkmez, Ahmet.
  • Akan, Serkan; University of Health Sciences. Sultan Abdulhamid Han Training and Research Hospital. Department of Urology. Istanbul. TR
  • Urkmez, Ahmet; University of Health Sciences. Haydarpasa Numune Training and Research Hospital. Department of Urology. Istanbul. TR
Rev Assoc Med Bras (1992) ; 66(4): 479-484, 2020. tab, graf
Article in English | SES-SP, LILACS | ID: biblio-1136241
ABSTRACT
SUMMARY OBJECTIVE We aimed to determine whether atherogenic dyslipidemia is associated with the disease and morbidity in our patients treated for Fournier's gangrene (FG). METHODS Sixty-two patients who were treated with the diagnosis of FG at our center between 2012 and 2017 were retrospectively screened. RESULTS The triglyceride values of the patients who required reconstructive surgery were statistically significantly higher than those of the patients for whom wound debridement and primary suturing was sufficient (p0.001). A total of 65.7% of the patients had normal triglyceride values in the group in which wound debridement and primary suturing was sufficient, while this rate was 22.2% in the group of patients who needed reconstructive surgery; the difference was statistically significant (p 0.002). The UFGSI score of those with triglyceride values higher than the normal range was statistically significantly higher (p0.006). The cut-off point for the triglyceride value for which Fournier's gangrene was more morbid and the probability of reconstructive surgery need was significantly higher, i.e., >233mg. CONCLUSION Our study has demonstrated that atherogenic dyslipidemia, especially hypertriglyceridemia, is an important factor affecting morbidity and associated with high patient care costs after hospitalization and discharge in FG.
RESUMO
RESUMO OBJETIVO Nosso objetivo foi determinar se as dislipidemias aterogênicas estão associadas à doença e à morbidade em nossos pacientes tratados para a gangrena de Fournier (GF). MÉTODOS Sessenta e dois pacientes tratados com o diagnóstico de GF em nosso centro entre 2012 e 2017 foram selecionados retrospectivamente. RESULTADOS Os valores de triglicérides dos pacientes que necessitaram de cirurgia reconstrutiva foram estatisticamente significativamente maiores em comparação com aqueles dos pacientes nos quais o desbridamento da ferida e a sutura primária foram suficientes (p0,001); 65,7% dos pacientes apresentaram valores normais de triglicérides no grupo em que desbridamento da ferida e sutura primária foram suficientes, enquanto que essa taxa foi de 22,2% no grupo de pacientes que necessitaram de cirurgia reconstrutiva, e a diferença foi estatisticamente significativa (p0,002). O escore UFGSI daqueles com valores de triglicerídeos acima da faixa normal foi estatisticamente significativamente maior (p0,006). O ponto de corte para o valor de triglicérides pelo qual a gangrena de Fournier era mais mórbida e a probabilidade de necessidade de cirurgia reconstrutiva era significativamente maior foi >233 mg. CONCLUSÃO Nosso estudo demonstrou que a dislipidemia aterogênica, especialmente a hipertrigliceridemia, é um fator importante que afeta a morbidade e os altos custos associados ao cuidado do paciente após hospitalização e alta na GF.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Fournier Gangrene / Dyslipidemias Type of study: Observational study / Risk factors Limits: Humans Language: English Journal: Rev Assoc Med Bras (1992) Year: 2020 Type: Article Institution/Affiliation country: University of Health Sciences/TR

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Full text: Available Index: LILACS (Americas) Main subject: Fournier Gangrene / Dyslipidemias Type of study: Observational study / Risk factors Limits: Humans Language: English Journal: Rev Assoc Med Bras (1992) Year: 2020 Type: Article Institution/Affiliation country: University of Health Sciences/TR