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The diagnostic process of covid-19 in the emergency department: laboratory and imaging methods
Guneysu, Fatih; Yurumez, Yusuf; Guclu, Ertugrul; Koroglu, Mehmet; Karacan, Alper; Guner, Necip Gokhan; Durgun, Yesim.
  • Guneysu, Fatih; Sakarya University. Training and Research Hospital. Clinic of Emergency Medicine. Sakarya. TR
  • Yurumez, Yusuf; Sakarya University. Faculty of Medicine. Department of Emergency Medicine. Sakarya. TR
  • Guclu, Ertugrul; Sakarya University. Faculty of Medicine. Department of Infectious Diseases. Sakarya. TR
  • Koroglu, Mehmet; Sakarya University. Faculty of Medicine. Department of Clinic Microbiology. Sakarya. TR
  • Karacan, Alper; Sakarya University. Faculty of Medicine. Department of Radiology. Sakarya. TR
  • Guner, Necip Gokhan; Sakarya University. Training and Research Hospital. Clinic of Emergency Medicine. Sakarya. TR
  • Durgun, Yesim; Sakarya University. Training and Research Hospital. Clinic of Emergency Medicine. Sakarya. TR
Rev Assoc Med Bras (1992) ; 66(Suppl 2): 58-64, 2020. tab
Article in English | SES-SP, LILACS | ID: biblio-1136398
ABSTRACT
SUMMARY OBJECTIVES The 2019 Novel coronavirus disease puts a serious burden on the health system. Therefore, the detection of particularly serious patients at an early stage is extremely important in terms of controlling the outbreak and improving the prognosis. We investigated the role of inflammatory markers studied in patients suspected of COVID-19 at an emergency department in predicting PCR and CT results. METHODS This retrospective study was carried out with 133 patients who were admitted between 13 March and 1st April 2020 with suspicion of COVID-19. The patients were divided into four groups according to CT and RT-PCR results and evaluated. RESULTS Considering all patients, no specific findings were found in the hematological and biochemical values of patients in the laboratory analyses. Although all of the results remained within the reference range, there was a significant difference in white blood cell, neutrophil, platelet, and lymphocyte values when the groups were compared [p = 0.000; p = 0.004; p = 0.022; p = 0.023]. CONCLUSION Laboratory is not specific enough in the pre-diagnosis. In addition, this result does not alter with PCR or CT positivity. However, minimal changes observed in laboratory results may be partially guiding in patients in whom both PCR and CT are positive.
RESUMO
RESUMO OBJETIVOS A nova doença de coronavírus de 2019 coloca um fardo sério para o sistema de saúde. Portanto, a detecção de pacientes especialmente graves em um estágio inicial é extremamente importante em termos de controle do surto e melhoria do prognóstico. Investigamos o papel dos marcadores inflamatórios estudados em pacientes suspeitos de COVID-19 no pronto-socorro na previsão de resultados de PCR e CT. MÉTODOS Este estudo retrospectivo foi realizado entre 133 pacientes que foram admitidos entre 13 de março e 1o de abril de 2020 com suspeita de COVID-19. Os pacientes foram divididos em quatro grupos de acordo com os resultados da TC e RT-PCR e avaliados. RESULTADOS Considerando todos os pacientes, não foram encontrados achados específicos nos valores hematológicos e bioquímicos dos pacientes em análises laboratoriais. Embora todos os resultados tenham permanecido dentro do intervalo de referência, houve uma diferença significativa nos valores de glóbulos brancos, neutrófilos, plaquetas e linfócitos quando os grupos foram comparados [p = 0,000; p = 0,004; p = 0,022; p = 0,023]. CONCLUSÃO O laboratório não é suficientemente específico no pré-diagnóstico. Além disso, este resultado não se altera com a positividade para PCR ou CT. No entanto, alterações mínimas observadas nos resultados laboratoriais podem ser parcialmente norteadoras em pacientes com PCR e CT positivos.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Pneumonia, Viral / Thorax / Tomography, X-Ray Computed / Coronavirus / Clinical Laboratory Techniques Type of study: Diagnostic study / Etiology study / Observational study / Prognostic study / Risk factors Limits: Humans Language: English Journal: Rev Assoc Med Bras (1992) Year: 2020 Type: Article Institution/Affiliation country: Sakarya University/TR

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Full text: Available Index: LILACS (Americas) Main subject: Pneumonia, Viral / Thorax / Tomography, X-Ray Computed / Coronavirus / Clinical Laboratory Techniques Type of study: Diagnostic study / Etiology study / Observational study / Prognostic study / Risk factors Limits: Humans Language: English Journal: Rev Assoc Med Bras (1992) Year: 2020 Type: Article Institution/Affiliation country: Sakarya University/TR