Cost analysis of smear microscopy and the Xpert assay for tuberculosis diagnosis: average turnaround time
Rev. Soc. Bras. Med. Trop
;
53: e20200314, 2020. tab, graf
Article
in English
| SES-SP, ColecionaSUS, LILACS
| ID: biblio-1136805
ABSTRACT
Abstract INTRODUCTION:
Rapid and accurate tuberculosis detection is critical for improving patient diagnosis and decreasing tuberculosis transmission. Molecular assays can significantly increase laboratory costs; therefore, the average time and economic impact should be evaluated before implementing a new technology. The aim of this study was to evaluate the cost and average turnaround time of smear microscopy and Xpert assay at a university hospital.METHODS:
The turnaround time and cost of the laboratory diagnosis of tuberculosis were calculated based on the mean cost and activity based costing (ABC).RESULTS:
The average turnaround time for smear microscopy was 16.6 hours while that for Xpert was 24.1 hours. The Xpert had a mean cost of USD 17.37 with an ABC of USD 10.86, while smear microscopy had a mean cost of USD 13.31 with an ABC of USD 6.01. The sensitivity of smear microscopy was 42.9% and its specificity was 99.1%, while the Xpert assay had a sensitivity of 100% and a specificity of 96.7%.CONCLUSIONS:
The Xpert assay has high accuracy; however, the turnaround time and cost of smear microscopy were lower than those of Xpert.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Tuberculosis, Pulmonary
/
Biological Assay
/
Pathology, Molecular
Type of study:
Diagnostic study
/
Health economic evaluation
Limits:
Humans
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Year:
2020
Type:
Article
Institution/Affiliation country:
Fundação Hospitalar do Estado de Minas Gerais/BR
/
Universidade Federal de Minas Gerais/BR
/
Universidade Federal do Rio de Janeiro/BR
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