Identification of plasmid IncQ1 and NTEKPC-IId harboring bla KPC-2 in isolates from Klebsiella pneumoniae infections in patients from Recife-PE, Brazil
Rev. Soc. Bras. Med. Trop
; 53: e20190526, 2020. tab, graf
Article
in En
| SES-SP, ColecionaSUS, LILACS
| ID: biblio-1136834
Responsible library:
BR1.1
ABSTRACT
Abstract INTRODUCTION:
This study investigated the genetic environment of bla KPC-2 in Klebsiella pnemoniae multi-drug resistant clinical isolates.METHODS:
Four carbapenemase gene isolates resistant to carbapenems, collected from infected patients from two hospitals in Brazil, were investigated using polymerase chain reaction and plasmid DNA sequencing.RESULTS:
The bla KPC-2 gene was located between ISKpn6 and a resolvase tnpR in the non-Tn4401 element (NTEKPC-IId). It was detected on a plasmid belonging to the IncQ1 group. CONCLUSIONS To our knowledge, this is the first report of the presence of the bla KPC-2 gene in the NTEKPC-IId element carried by plasmid IncQ1 from infections in Brazil.Key words
Full text:
1
Index:
LILACS
Main subject:
Beta-Lactamases
/
Klebsiella Infections
/
Klebsiella pneumoniae
/
Anti-Bacterial Agents
Type of study:
Diagnostic_studies
Limits:
Humans
Country/Region as subject:
America do sul
/
Brasil
Language:
En
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
MEDICINA TROPICAL
Year:
2020
Type:
Article