The use of Gene-Xpert MTB RIF in the diagnosis of extrapulmonary tuberculosis in childhood and adolescence
Rev. Soc. Bras. Med. Trop
;
53: e20200104, 2020. tab, graf
Article
in English
| SES-SP, ColecionaSUS, LILACS
| ID: biblio-1136907
ABSTRACT
Abstract INTRODUCTION:
Gene-Xpert MTB RIF (Xpert) is based on nucleic acid amplification by real-time polymerase chain reaction, which allows for the identification of Mycobacterium tuberculosis and rifampin resistance. We describe the use of Xpert for extrapulmonary tuberculosis (EPTB) in children and adolescents.METHODS:
A case series of two reference centers in Rio de Janeiro from 2014-2019.RESULTS:
The final diagnosis of EPTB was established in 11/36 (31%) patients, with five cases detectable by Xpert. For lymph node evaluation (9/11), diagnosis by Xpert occurred in 5/9 patients, all with caseous aspects.CONCLUSIONS:
Xpert can facilitate the rapid diagnosis of lymph node tuberculosis.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Tuberculosis
/
Mycobacterium tuberculosis
Type of study:
Diagnostic study
Limits:
Adolescent
/
Child
/
Child, preschool
/
Humans
/
Infant
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Year:
2020
Type:
Article
Institution/Affiliation country:
Universidade Federal do Rio de Janeiro/BR
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