Predictive value of neutrophil-lymphocyte ratio for long-term cardiovascular event following coronary artery bypass grafting
Rev. bras. cir. cardiovasc
;
35(3): 274-284, May-June 2020. tab, graf
Article
in English
| LILACS, SES-SP
| ID: biblio-1137258
ABSTRACT
Abstract Objective:
To investigate the predictive value of preoperative neutrophil-lymphocyte ratio (NLR) for long-term major adverse cardiac and cerebrovascular events (MACCE), which have not yet been well described, in patients undergoing coronary artery bypass grafting (CABG).Methods:
The records of 751 consecutive patients who underwent elective CABG between January 2008 and January 2010 were retrospectively enrolled and stratified according to quartiles of preoperative NLR. At 7.8-year follow-up, MACCE was considered as an endpoint.Results:
Overall MACCE was 11.6% of all cases. Long-term myocardial infarction, percutaneous coronary intervention, stroke and cardiovascular mortality were found associated with the upper NLR quartile (P<0.001, P<0.001, P=0.005, P<0.001, respectively). In multivariate analysis, NLR on admission remained an independent predictor of long-term MACCE (OR 1.087, 95% CI 1.026-1.151; P=0.004), in all EuroSCORE risk groups (P<0.001; P<0.001; P=0.029). The receiver operating characteristic (ROC) curve analyses revealed an NLR cut-off value of 4.32 predicting MACCE.Conclusion:
NLR is a useful and readily available predictive marker of long-term MACCE following CABG, independent of the EuroSCORE.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Coronary Artery Disease
/
Percutaneous Coronary Intervention
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
Rev. bras. cir. cardiovasc
Year:
2020
Type:
Article
Institution/Affiliation country:
Abant Izzet Baysal University/TR
/
Bahcesehir University/TR
/
Ceylan International Hospital/TR
/
Meddem Hospital/TR
/
Medicana Bursa Hospital/TR
/
Samsun Hospital for Education and Research/TR
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