Cardiac shock wave therapy for coronary heart disease: an updated meta-analysis
Rev. bras. cir. cardiovasc
;
35(5): 741-756, Sept.-Oct. 2020. tab, graf
Article
in English
| LILACS, SES-SP
| ID: biblio-1137341
ABSTRACT
Abstract Introduction:
The aim of this article is to study the efficacy and safety of cardiac shock wave therapy (CSWT) in the treatment of coronary heart disease (CAD).Methods:
A comprehensive search of electronic databases and a manual search of conference papers and abstracts were performed until September 30, 2018. The studies using RevMan 5.3 and STATA 14.0 softwares were reviewed, and meta-analyses were performed on 13 indicators, such as a six-min walking distance test (6MWT), New York Heart Association (NYHA) functional class, Seattle Angina Questionnaire (SAQ) score, angina class (Canadian Cardiology Society [CCS]), etc.Results:
A total of 26 articles were included. The total patient population was 855, of which 781 patients were treated with CSWT. Meta-analyses indicated that 6MWT (mean difference [MD] 75.64, 95% confidence interval [CI] 49.03, 102.25, P<0.00001) and NYHA (MD -0.70, 95% CI -0.92) in the CSWT group were comparable to those in the conventional revascularization group (MD -0.70, 95% CI -0.92, -0.49, P<0.00001). SAQ (MD 10.75, 95% CI 6.66, 14.83, P<0.00001), CCS (MD -0.99, 95% CI -1.13, -0.84, P<0.00001), nitrate dosage (MD -1.84, 95% CI -2.77, -1.12, P<0.00001), LVEF (MD 3.77, 95% CI 2.17, 5.37, P<0.00001), and SSS (MD -4.29, 95% CI -5.61, -2.96, P<0.00001), SRS (MD -2.90, 95% CI -4.85, -0.95, P=0.004), and the exercise test (standard mean difference 0.57, 95% CI 0.12, 1.02, P=0.01) all showed significant differences.Conclusion:
CSWT may offer beneficial effects to patients with CAD, but more large-scale clinical studies are needed to further verify its therapeutic effect.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Coronary Disease
/
Extracorporeal Shockwave Therapy
Type of study:
Etiology study
/
Practice guideline
/
Incidence study
/
Observational study
/
Risk factors
/
Systematic reviews
Limits:
Humans
/
Male
Country/Region as subject:
North America
Language:
English
Journal:
Rev. bras. cir. cardiovasc
Year:
2020
Type:
Article
Institution/Affiliation country:
Changji Hui Autonomous Prefecture Peoples Hospital/CN
/
Xinjiang Medical University/CN
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