Filtrado glomerular y enfermedad cardiovascular en hipertensos / Glomerular filtration and cardiovascular disease in hypertensive patients

RESUMEN

Introducción: La enfermedad renal crónica expresada por un filtrado glomerular disminuido se asocia a un mayor riesgo de enfermedad cardiovascular y a mayor progresión del daño renal. Es muy recomendable como método disponible y económico para evaluar el riesgo cardiovascular en hipertensos. Objetivo: Evaluar el daño renal y la enfermedad cardiovascular en hipertensos del Policlínico Managua. Método: Se estudiaron 1037 pacientes hipertensos. Se calculó el filtrado glomerular según el Modification Diet Renal Disease Study. Se estudiaron variables demográficas, factores de riesgo vascular y presencia de enfermedad cardiovascular. Se definió 60 mil/min/1,73m2 para el filtrado glomerular disminuido. Resultados: De los pacientes estudiados, 28,5 por ciento presentaron filtrado glomerular disminuido, mostrando mayor prevalencia de enfermedad cardiovascular que aquellos sin daño renal (53,4 por ciento vs 33,9 por ciento; OR 2,19 IC 95 por ciento 1,51-2,82; p ; 0,001). Conclusiones: Este estudio muestra que la enfermedad renal crónica se asocia a mayor prevalencia de enfermedad cardiovascular, siendo un factor de riesgo cardiovascular mayor(AU)

ABSTRACT

Introduction: Chronic kidney disease expressed by decreased glomerular filtration rate is associated with high risk of cardiovascular disease and great progression of kidney damage. This filtration is highly recommended as an available and inexpensive method to assess cardiovascular risk in hypertensive patients. Objective: To assess kidney damage and cardiovascular disease in hypertensive patients at Managua Polyclinic. Method: This research included 1037 hypertensive patients. Glomerular filtration was calculated according to the Modification Diet Renal Disease Study. Demographic variables, vascular risk factors, and the presence of cardiovascular disease were studied. The decreased glomerular filtration was defined for ;60 thousand/min/1.73m2. Results: 28.5 percent of the studied patients showed decreased glomerular filtration, higher prevalence of cardiovascular disease than those without kidney damage (53.4 percent ;vs. 33.9 percent; OR 2.19 95 percent CI 1.51-2, 82; p ;0.001). Conclusions: This study showed that chronic kidney disease is associated with high prevalence of cardiovascular disease, which establishes higher cardiovascular risk factor(AU)