Factores asociados a respuesta favorable de tratamiento corticoidal en pacientes con polirradiculoneuropatía desmielinizante inflamatoria crónica / Variables associated with a good response to steroids in chronic inflammatory demyelinating polyradiculoneuropathy
Rev. méd. Chile
;
148(5): 594-601, mayo 2020. tab, graf
Article
in Spanish
| LILACS
| ID: biblio-1139343
ABSTRACT
Background:
The treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is based on corticosteroids, immunoglobulin and plasmapheresis. In our Health System, corticosteroids are commonly used as first line therapy for economic reasons and accessibility. However, the factors associated with a good response are not well known.Aim:
To assess the association of demographic, clinical and laboratory variables with a favorable response to corticosteroid therapy in patients with CIDP. Material andMethods:
Observational, descriptive, longitudinal and retrospective study of 33 patients with a diagnosis of typical, definitive or probable CIDP, treated with corticosteroids for at least six months.Results:
Twenty-three patients had a good clinical response to corticosteroid treatment and 10 were non-responders. The variables significantly associated with a good response to steroids were a disease lasting less than 1 year prior to the start of treatment, the absence of axonal damage in electromyography a relapsing-recurrent course and a favorable response within two months of treatment.Conclusions:
Most of these patients with CIDP had good response to corticosteroid therapy.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Adrenal Cortex Hormones
/
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Type of study:
Observational study
/
Risk factors
Limits:
Humans
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2020
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Hospital Clínico Regional de Concepción Dr. Guillermo Grant Benavente/CL
/
Universidad de Concepción/CL
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