Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study
São Paulo med. j
;
138(2): 152-157, Mar.-Apr. 2020. tab, graf
Article
in English
| LILACS, SES-SP
| ID: biblio-1139679
ABSTRACT
ABSTRACT BACKGROUND:
Sarcopenia is a common complication in patients with cirrhosis and may lead to increased morbidity and mortality.OBJECTIVE:
To investigate the prevalence of sarcopenia and its association with disease severity scores, among patients with cirrhosis. DESIGN ANDSETTING:
Observational and retrospective cohort study carried out in a tertiary-care hospital in southern Brazil.METHODS:
This study was conducted among patients with chronic liver disease who were followed up at the gastroenterology and hepatology outpatient clinic of a tertiary-care hospital in southern Brazil and who underwent computed tomography scans of the abdomen through any indication.RESULTS:
We included 83 patients in the study. In the population evaluated, there was a predominance of males (57.80%) and the mean age was 56 years. Hepatitis B or C virus was present in the genesis of the disease in 34.9% of the cases, followed by an etiology of alcohol abuse (30.1%). Sarcopenia was diagnosed in 41 (49.4%) of the patients when the cutoff point for cirrhotic patients was used. There was no significant correlation between the Child-Pugh and MELD severity scores and the occurrence of sarcopenia.CONCLUSION:
Sarcopenia presents high prevalence among patients with chronic liver disease, without any association with predictors of severity.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Sarcopenia
/
Liver Cirrhosis
Type of study:
Observational study
/
Prevalence study
/
Prognostic study
/
Risk factors
Limits:
Child
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
São Paulo med. j
Year:
2020
Type:
Article
Institution/Affiliation country:
Santa Casa de Misericórdia de Porto Alegre/BR
/
Unimed Porto Alegre/BR
/
Universidade Federal de Ciências da Saúde de Porto Alegre/BR
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