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Presencia de nódulos tiroideos en pacientes con síndrome metabólico en un hospital de tercer nivel de atención peruano / Presence of thyroid nodes in patients with metabolic syndrome in a Peruvian tertiary care hospital
Noriega-Ruiz, Victor; Torres-Samame, Liliana; Huachin-Soto, Miluska; Villena, Jaime; Loza, Javier.
  • Noriega-Ruiz, Victor; Hospital Cayetano Heredia. Lima. PE
  • Torres-Samame, Liliana; Hospital Regional de Lambayeque. Chiclayo. PE
  • Huachin-Soto, Miluska; Hospital Cayetano Heredia. Lima. PE
  • Villena, Jaime; Hospital Cayetano Heredia. Lima. PE
  • Loza, Javier; Universidad Peruana Cayetano Heredia. Facultad de Medicina. Lima. PE
Acta méd. peru ; 37(3): 312-317, jul-sep 2020. tab
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1142016
RESUMEN
RESUMEN Objetivo: comparar la frecuencia de enfermedad nodular tiroidea (ENT) en pacientes con síndrome metabólico (SM) y en pacientes sin SM en un área yodosuficiente. Materiales y métodos: estudio analítico, de casos y controles, comparativo de grupos pareados. Fueron 40 pacientes con SM y 40 controles, pareados por edad y sexo, los cuales acudieron al servicio de Endocrinología del Hospital Cayetano Heredia, Lima - Perú. El peso, talla y la presión arterial fueron tomadas de la historia clínica. Se evaluó el perímetro abdominal y la presencia de acantosis nigricans. Se midió perfil lipídico, glucosa basal y TSH. Se realizó ecografía tiroidea a todos los participantes. Se midió el volumen tiroideo y se consideró clínicamente significativo a nódulos tiroideos > 5 mm. Resultados: el 80 % de la población estudiada en ambos grupos fueron mujeres. Hubo diferencias significativas en el hábito tabáquico, la acantosis nigricans, la TSH, el volumen tiroideo, peso, índice de masa corporal, perímetro abdominal, presión diastólica, glucosa basal, HDL-colesterol y triglicéridos entre ambos grupos. La ENT fue más frecuente en los pacientes con SM que en los pacientes sin SM (40% vs. 12,5% respectivamente, p = 0,015). El odds ratio (OR) para presentar nódulos tiroideos en presencia de SM fue de 4,66 (intervalo de confianza al 95%: 1,34 - 16,24). Hubo diferencia significativa en el volumen tiroideo entre ambos grupos (p = 0,039). Conclusión: en una población de una zona yodosuficiente, el SM estuvo asociado a ENT y al incremento del volumen tiroideo.
ABSTRACT
ABSTRACT: Objective : To compare the frequency of thyroid node disease (TND) in patients with metabolic syndrome (MS) and in patients without metabolic syndrome in an area with good iodine supply. Materials and Methods : This is an analytical comparative case- control study performed in paired groups. There were 40 patients with MS and 40 controls attending the Endocrinology service in Cayetano Heredia Hospital in Lima, Peru, who were paired according to age and sex. Weight, height, and blood pressure measurements were taken from clinical records. Abdominal circumference was measured, and the presence of acanthosis nigricans was determined. Lipid profile, baseline blood glucose and TSH were determined. Thyroid ultrasonography was performed in all participants. Thyroid volume values were recorded and thyroid nodes measuring >5-mm were considered as clinically significant. Results : Eighty per cent of the studied population in both groups was women. There were significant differences in tobacco use, acanthosis nigricans, TSH levels, thyroid volume, weight, body mass index, abdominal circumference, diastolic blood pressure, baseline blood glucose, HDL-cholesterol and triglyceride levels between both groups. TND was more frequent in those patients with MS compared to patients with no MS (40% vs. 12.5%, respectively; p= 0.015). The odds ratio (OR) for having thyroid nodes in the presence of MS was 4.66 (95% confidence interval: 1.34-16.24). There were significant differences in thyroid volume for both groups (p= 0.039). Conclusion : In an area with good iodine supply, MS was associated to TND to with an increased thyroid volume.


Full text: Available Index: LILACS (Americas) Type of study: Observational study / Risk factors Country/Region as subject: South America / Peru Language: Spanish Journal: Acta méd. peru Journal subject: Medicine Year: 2020 Type: Article Affiliation country: Peru Institution/Affiliation country: Hospital Cayetano Heredia/PE / Hospital Regional de Lambayeque/PE / Universidad Peruana Cayetano Heredia/PE

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Full text: Available Index: LILACS (Americas) Type of study: Observational study / Risk factors Country/Region as subject: South America / Peru Language: Spanish Journal: Acta méd. peru Journal subject: Medicine Year: 2020 Type: Article Affiliation country: Peru Institution/Affiliation country: Hospital Cayetano Heredia/PE / Hospital Regional de Lambayeque/PE / Universidad Peruana Cayetano Heredia/PE