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First report of a blaNDM-resistant gene in a Klebsiella aerogenes clinical isolate from Brazil
Soares, Cynthia Regina Pedrosa; Oliveira-Júnior, Jorge Belém; Firmo, Elza Ferreira.
Affiliation
  • Soares, Cynthia Regina Pedrosa; Universidade Federal de Pernambuco. Departamento de Medicina Tropical. Recife. BR
  • Oliveira-Júnior, Jorge Belém; Instituto Aggeu Magalhães. Laboratório de Biologia Molecular e Celular. Departamento de Parasitologia. Recife. BR
  • Firmo, Elza Ferreira; Universidade Federal de Pernambuco. Departamento de Medicina Tropical. Recife. BR
Rev. Soc. Bras. Med. Trop ; 54: e02622020, 2021.
Article in En | SES-SP, ColecionaSUS, LILACS | ID: biblio-1143877
Responsible library: BR1.1
ABSTRACT
Abstract

INTRODUCTION:

Carbapenemase-resistant enterobacteria that produce the bla NDM gene are found worldwide. However, this is the first report of blaNDM in Klebsiella aerogenes in Brazil.

METHODS:

The identification of bacterial species was performed using anautomated system and confirmed by biochemical tests, 16S rRNA gene sequencing, and detection of resistance genes.

RESULTS:

The clinical isolate showed minimum inhibitory concentration resistance to meropenem and polymyxin B at 8mg/L and 4mg/L, respectively. Only the blaNDM gene was detected.

CONCLUSIONS:

The current report of the blaNDM gene in isolated MDR enterobacteria indicates that this gene can spread silently in a hospital setting.
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Full text: 1 Index: LILACS Main subject: Enterobacter aerogenes Country/Region as subject: America do sul / Brasil Language: En Journal: Rev. Soc. Bras. Med. Trop Journal subject: MEDICINA TROPICAL Year: 2021 Type: Article
Fulltext
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Full text: 1 Index: LILACS Main subject: Enterobacter aerogenes Country/Region as subject: America do sul / Brasil Language: En Journal: Rev. Soc. Bras. Med. Trop Journal subject: MEDICINA TROPICAL Year: 2021 Type: Article