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Acute uveitis: A rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis
Pandey, Krishna; Pal, Biplab; Topno, Roshan Kamal; Lal, Chandra Shekhar; Das, Vidya Nand Rabi; Das, Pradeep.
  • Pandey, Krishna; Indian Council of Medical Research. Rajendra Memorial Research Institute of Medical Sciences. Department of Clinical Medicine. Agamkuan. IN
  • Pal, Biplab; Lovely Professional University. Department of Pharmacology. Jalandhar - Delhi G.T. Road. Phagwara. IN
  • Topno, Roshan Kamal; Indian Council of Medical Research. Rajendra Memorial Research Institute of Medical Sciences. Department of Epidemiology. Agamkuan. IN
  • Lal, Chandra Shekhar; Indian Council of Medical Research. Rajendra Memorial Research Institute of Medical Sciences. Department of Biochemistry. Agamkuan. IN
  • Das, Vidya Nand Rabi; Indian Council of Medical Research. Rajendra Memorial Research Institute of Medical Sciences. Department of Clinical Medicine. Agamkuan. IN
  • Das, Pradeep; Indian Council of Medical Research. Rajendra Memorial Research Institute of Medical Sciences. Department of Molecular Biology. Agamkuan. IN
Rev. Soc. Bras. Med. Trop ; 54: e20200208, 2021. graf
Article in English | SES-SP, ColecionaSUS, LILACS | ID: biblio-1143878
ABSTRACT
Abstract Post-kala-azar dermal leishmaniasis is a skin disorder occurring in 5-10% of visceral leishmaniasis patients after treatment with miltefosine,the first-line drug for this skin disorder. We reported a case of acute anterior uveitis,a rare adverse effect, experienced by a patient treated with miltefosine for post-kala-azar dermal leishmaniasis. This adverse effect developed after 15 days of miltefosine consumption, and the patient himself discontinued the treatment. The ophthalmic complication was completely resolved with antibiotics and steroid eye drops. After recovery from the ophthalmic complication, the patient was successfully treated with liposomal amphotericin B for the skin lesions.
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Full text: Available Index: LILACS (Americas) Main subject: Uveitis / Leishmaniasis, Cutaneous / Leishmaniasis, Visceral / Antiprotozoal Agents Limits: Humans Language: English Journal: Rev. Soc. Bras. Med. Trop Year: 2021 Type: Article Institution/Affiliation country: Indian Council of Medical Research/IN / Lovely Professional University/IN

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Full text: Available Index: LILACS (Americas) Main subject: Uveitis / Leishmaniasis, Cutaneous / Leishmaniasis, Visceral / Antiprotozoal Agents Limits: Humans Language: English Journal: Rev. Soc. Bras. Med. Trop Year: 2021 Type: Article Institution/Affiliation country: Indian Council of Medical Research/IN / Lovely Professional University/IN