Reactivation of Chagas disease after autologous hematopoietic stem cell transplantation
Rev. Soc. Bras. Med. Trop
;
54: e20200143, 2021. graf
Article
in English
| SES-SP, ColecionaSUS, LILACS
| ID: biblio-1143881
ABSTRACT
Abstract Chagas disease (CD) is a protozoan zoonosis caused by Trypanosoma cruzi. Reactivation of CD occurs via drug-induced immunosuppression before and during transplantation. Here, we report the case of a 62-year-old man diagnosed with classic Hodgkin lymphoma who received highly aggressive conditioning chemotherapy before undergoing stem cell transplantation (SCT). The patient tested positive for CD in pre-transplantation evaluation. The patient exhibited persistent fever and elevated C-reactive protein levels before and after SCT, and was treated with antibiotics. Micro-Strout test showed evidence of trypomastigotes and he was treated with benznidazole until tested negative. Post-transplantation seropositive patients should be screened for possible reactivation.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Trypanosoma cruzi
/
Chagas Disease
/
Hematopoietic Stem Cell Transplantation
Limits:
Animals
/
Humans
/
Male
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Year:
2021
Type:
Article
Institution/Affiliation country:
Clínica FOSCAL/CO
/
Universidad Autónoma de Bucaramanga/CO
Similar
MEDLINE
...
LILACS
LIS