Selective activity of diselenides against Aedes aegypti (Diptera: Culicidae) larvae
Rev. Soc. Bras. Med. Trop
; 54: e20200146, 2021. tab
Article
in En
| SES-SP, ColecionaSUS, LILACS
| ID: biblio-1143889
Responsible library:
BR1.1
ABSTRACT
Abstract INTRODUCTION:
Aedes aegypti (L.) is the major vector of arboviruses that causes serious public health concerns in tropical and subtropical countries.METHODS:
We examined the larvicidal activity of 1,2-diphenyldiselenide [(PhSe)2] and 1,2-bis(4-chlorophenyl) diselenide [(p-ClPhSe)2] and determine its toxicity to different non-target organisms.RESULTS:
(PhSe)2 and (p-ClPhSe)2 killed Ae. aegypti L3 larvae with LC50/24h values of 65.63 µM (20.48 mg/L) and 355.19 µM (135.33 mg/L), respectively. (PhSe)2 was not toxic to the four model organisms.CONCLUSIONS:
(PhSe)2 is a larvicidal compound with selective action against Ae. aegypti larvae. The mechanisms of action of (PhSe)2 under field conditions remain to be investigated.Key words
Full text:
1
Index:
LILACS
Main subject:
Aedes
/
Insecticides
Limits:
Animals
Language:
En
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
MEDICINA TROPICAL
Year:
2021
Type:
Article