AIDS-related progressive multifocal leukoencephalopathy
Rev. Soc. Bras. Med. Trop
;
54: e02522020, 2021. tab
Article
in English
| SES-SP, ColecionaSUS, LILACS
| ID: biblio-1143893
ABSTRACT
Abstract INTRODUCTION:
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by reactivation of JC virus (JCV).METHODS:
We described the profile of laboratory-confirmed PML cases among AIDS patients.RESULTS:
A total of 43 HIV patients with clinical conditions compatible with PML were obtained; 5 cases were confirmed by JCV testing. The main clinical finding was mental confusion. Median CD4 count was 54 cells/mm³.CONCLUSIONS:
Three of the five confirmed PML cases died; the time between diagnosis and death was 2, 5, and 6 months. It is important to consider JCV infection as a differential diagnosis.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
HIV Infections
/
Acquired Immunodeficiency Syndrome
/
Leukoencephalopathy, Progressive Multifocal
/
JC Virus
Limits:
Humans
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Year:
2021
Type:
Article
Institution/Affiliation country:
Secretaria de Estado da Saúde de Goiás/BR
/
Universidade Federal de Goiás/BR
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