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Multiresistant microorganism infection in newborns at an intermediate neonatal care unit and intensive care unit of reference: cross-sectional study / Infecção por microrganismo multirresistente em recém-nascidos na unidade de cuidados intermediários neonatais e unidade de cuidados intensivos de referência: estudo transversal
Lima, Flávio Henrique Alves de; Paula, Cácia Régia de; Pacheco, Jade Alves de Souza; Pelazza, Bruno Bordin; Mendonça, Guilherme Silva de; Barbosa, Maria Alves; Silva, Marinésia Aparecida da.
  • Lima, Flávio Henrique Alves de; Federal University of Goiás. Jataí. BR
  • Paula, Cácia Régia de; Federal University of Jataí. Jataí. BR
  • Pacheco, Jade Alves de Souza; Federal University of Goiás, Faculty of Medicine. Jataí. BR
  • Pelazza, Bruno Bordin; University of the Midwest. Midwest. US
  • Mendonça, Guilherme Silva de; Institution Federal University of Uberlândia. Uberlândia. BR
  • Barbosa, Maria Alves; Federal University of Goiás, Faculty of Medicine. Jataí. BR
  • Silva, Marinésia Aparecida da; University of São Paulo. São Paulo. BR
Biosci. j. (Online) ; 36(6): 2307-2314, 01-11-2020. tab
Article in English | LILACS | ID: biblio-1148392
ABSTRACT
The objective was to describe the infection profile of multidrug-resistant organisms of newborns (NB), admitted to the neonatal intermediate care unit and the intensive care unit. It was a descriptive cross-sectional study of epidemiological nature, composed of 931 medical records and/or Hospital Infection Control Committee notification records, during the period of June to September 2012. Eight hundred and seventy newborns (NB) were admitted to the neonatal intensive care units and to intermediate care, with a final sample of 45 NB presenting bloodstream infections (BSI) caused by multiresistant microorganisms. From the analyses, the following results were highlighted gestational age < 37 weeks in 42 (93.3%); low weight at birth between < 750g to 1.499g. The profile for resistance to enterobacteriaceae was 100% for cefepime and ceftazidime concerning non-fermenting gram-negative bacteria, it was found that (100%) of P.aeruginosa was resistant to aztreonam, (100%) of S. maltophilia resistant to ceftazidime and to gentamycin, however, (1.1%) of S. aureus isolates were resistant to oxacillin and (12.5%) of S. haemolyticus demonstrated a confirmed resistance to vancomycin. These results are worrying and express the importance of correct monitoring, and the need for producing a propaedeutic protocol in consensus with the multiprofessional team through the Hospital Infection Control Committee and managers, which is then implemented and regularly assessed by the service.
RESUMO
Objetivou-se descrever a infecção por microorganismo multirresistente em recém-nascidos na unidade de cuidados intermediários neonatais e unidade de cuidados intensivos de referência. Tratou-se de estudo transversal de natureza epidemiológica, composto por 931 fichas e/ou prontuários de notificação da Comissão de Controle de Infecção Hospitalar (CCIH), no período junho a setembro de 2012. Foram 870 recém-nascidos (RN), admitidos nas unidades de terapia intensiva neonatal e de cuidados intermediários, como amostra final 45 RN apresentaram infecção de corrente sanguínea por microorganismo multirresistente. Dessas análises destacam-se os

resultados:

idade gestacional < 37 semanas em 42 (93,3%); baixo peso ao nascer entre < 750g a 1.499g. O perfil de resistência à enterobactérias foi de 100% para o cefepime e ceftazidime, e para as bactérias gram-negativas não fermentadoras, verificou-se que (100%) da P.aeruginosa era resistente ao aztreonam, (100%) de S.maltophilia resistente à ceftazidima e à gentamicina; Entretanto, (1,1%) dos isolados de S. aureus eram resistentes à oxacilina e (12,5%) de S. haemolyticus conferiu resistência à vancomicina. Esses resultados são preocupantes e demonstram a relevância do monitoramento, propondo a elaboração de protocolo propedêutico em consenso com a equipe multiprofissional, com a CCIH e gestores a ser implementado e avaliado, regularmente pelo serviço.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Drug Resistance, Microbial / Infant, Newborn / Child Health Services / Infections Type of study: Practice guideline / Observational study / Prevalence study Language: English Journal: Biosci. j. (Online) Journal subject: Agricultura / Disciplinas das Ciˆncias Biol¢gicas / Pesquisa Interdisciplinar Year: 2020 Type: Article Affiliation country: Brazil / United States Institution/Affiliation country: Federal University of Goiás/BR / Federal University of Goiás, Faculty of Medicine/BR / Federal University of Jataí/BR / Institution Federal University of Uberlândia/BR / University of São Paulo/BR / University of the Midwest/US

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Full text: Available Index: LILACS (Americas) Main subject: Drug Resistance, Microbial / Infant, Newborn / Child Health Services / Infections Type of study: Practice guideline / Observational study / Prevalence study Language: English Journal: Biosci. j. (Online) Journal subject: Agricultura / Disciplinas das Ciˆncias Biol¢gicas / Pesquisa Interdisciplinar Year: 2020 Type: Article Affiliation country: Brazil / United States Institution/Affiliation country: Federal University of Goiás/BR / Federal University of Goiás, Faculty of Medicine/BR / Federal University of Jataí/BR / Institution Federal University of Uberlândia/BR / University of São Paulo/BR / University of the Midwest/US