Sarcopenia, bone mineral density, and vitamin D: EpiFloripa aging study 2013/2014 / Sarcopenia, densidade mineral óssea e vitamina D: Estudo EpiFloripa Idoso 2013/2014
Geriatr., Gerontol. Aging (Online)
; 14(4): 282-289, 31-12-2020.
Article
in En
| LILACS
| ID: biblio-1151615
Responsible library:
BR275.1
Localization: BR275.1
ABSTRACT
OBJECTIVE:
To verify associations between osteopenia/osteoporosis and vitamin D and sarcopenia in the older adult population of Florianópolis, Brazil.METHODS:
A cross-sectional population-based study, with 604 older adults (60 years and over). The appendicular muscle mass index (AMMI) was used to identify sarcopenia, with cutoffs of AMMI (Kg/m2) < 7.26 kg/m2 for men and < 5.50 kg/m2 for women indicating inadequate values (sarcopenia). The independent variable osteopenia/osteoporosis was measured using bone mineral density (BMD, g/cm2) T-Scores for whole body BMD, lumbar spine BMD, and femoral neck BMD, categorized as normal (BMD > -1 SD) or osteopenia/osteoporosis (BMD < -1 SD from the mean of the young adult reference population). Fasting serum samples were collected and assayed using the microparticle chemiluminescence (CMIA)/Liaison method. Vitamin D concentrations of < 30 ng/mL were defined as hypovitaminosis. Crude and adjusted logistic regression analyses were performed.RESULTS:
Osteopenia/osteoporosis in the lumbar spine and femoral neck were associated with higher odds of sarcopenia in women and men. Osteopenia/osteoporosis in the whole body was associated with sarcopenia in women only. Vitamin D was not associated with sarcopenia in either sex.CONCLUSIONS:
Having osteopenia/osteoporosis was associated with sarcopenia in this older adult population.RESUMO
OBJETIVO:
Verificar a associação entre osteopenia/osteoporose e vitamina D com a sarcopenia na população idosa de Florianópolis.METODOLOGIA:
Estudo transversal de base populacional, com 604 idosos (60 anos ou mais). O índice de massa muscular apendicular (IMMA) foi utilizado para identificar a sarcopenia, onde o IMMA (Kg/m2) < 7,26 kg/m2 para homens e < 5,50 kg/m2 para mulheres indicava valores inadequados (sarcopenia). A variável independente osteopenia/ osteoporose foi medida pela densidade mineral óssea (DMO, g/cm2), foram calculados os T-escores para DMO corporal total, DMO da coluna lombar e DMO do colo femoral, categorizados como normais (DMO até -1 DP) ou osteopenia/osteoporose (DMO < -1 DP da média da população adulta jovem de referência). Amostras de soro em jejum foram coletadas pelo método de quimioluminescência de micropartículas (CMIA)/Liaison. Concentrações de vitamina D < 30 ng/mL foram definidas como hipovitaminose. Foi realizada análise de regressão logística bruta e ajustada.RESULTADOS:
Osteopenia/osteoporose na coluna lombar e colo do fêmur foram associadas a maiores chances de sarcopenia em mulheres e homens. Osteopenia/ osteoporose no corpo total foi associada à sarcopenia apenas em mulheres. A vitamina D não foi associada à sarcopenia em ambos os sexos.CONCLUSÕES:
A presença de osteopenia/osteoporose associou-se à sarcopenia nesta população de idosos.Key words
Full text:
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Index:
LILACS
Main subject:
Osteoporosis
/
Bone Diseases, Metabolic
/
Epidemiologic Factors
/
Sarcopenia
Type of study:
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
Limits:
Aged
/
Humans
Country/Region as subject:
America do sul
/
Brasil
Language:
En
Journal:
Geriatr., Gerontol. Aging (Online)
Journal subject:
Envelhecimento
/
Geriatria
/
Medicina Cl¡nica
/
Patologia
Year:
2020
Type:
Article