Brazilian recommendations for the use of nonsteroidal anti-inflammatory drugs in patients with axial spondyloarthritis
Adv Rheumatol
;
61: 4, 2021. tab, graf
Article
in English
| LILACS
| ID: biblio-1152735
ABSTRACT
Abstract Spondyloarthritis (SpA) is a group of chronic inflammatory systemic diseases characterized by axial and/or peripheral joints inflammation, as well as extra-articular manifestations. Over some decades, nonsteroidal anti-inflammatory drugs (NSAIDs) have been the basis for the pharmacological treatment of patients with axial spondyloarthritis (axSpA). However, the emergence of the immunobiologic agents brought up the discussion about the role of NSAIDs in the management of these patients. The objective of this guideline is to provide recommendations for the use of NSAIDs for the treatment of axSpA. A panel of experts from the Brazilian Society of Rheumatology conducted a systematic review and meta-analysis of randomized clinical trials for 15 predefined questions. The Grading of Recommendations, Assessment, Development and Evaluation methodology to assess the quality of evidence and formulate recommendations were used, and at least 70% agreement of the voting panel was needed. Fourteen recommendations for the use of NSAIDs in the treatment of patients with axSpA were elaborated. The purpose of these recommendations is to support clinicians' decision making, without taking out his/her autonomy when prescribing for an individual patient.(AU)
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Spondylitis, Ankylosing
/
Anti-Inflammatory Agents, Non-Steroidal
/
Guidelines as Topic
/
Decision Making
Type of study:
Controlled clinical trial
/
Practice guideline
/
Prognostic study
/
Qualitative research
/
Systematic reviews
Limits:
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Adv Rheumatol
Journal subject:
Artrite
/
Reumatologia
Year:
2021
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Hospital Estadual Geral de Goiania/BR
/
Hospital Heliópolis/BR
/
Hospital do Servidor Público do Estado de São Paulo/BR
/
Pontifícia Universidade Católica (PUC) de Campinas/BR
/
Pontifícia Universidade Católica (PUC) de Porto Alegre/BR
/
Pontifícia Universidade Católica (PUC) de Sorocaba/BR
/
Pontifícia Universidade Católica de Campinas/BR
/
Ribeirão Preto/BR
/
Santa Casa de Misericórdia (SCM) de São Paulo/BR
/
Santa Casa de Misericórdia (SCM) do Rio de Janeiro/BR
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