Update on human papilloma virus - part I: epidemiology, pathogenesis, and clinical spectrum
An. bras. dermatol
;
96(1): 1-16, Jan.-Feb. 2021. tab, graf
Article
in English
| LILACS
| ID: biblio-1152799
ABSTRACT
Abstract Infection with human papilloma virus (HPV) is related to a great number of cutaneous and mucosal manifestations. The spectrum of HPV ranges from inapparent infections, through various clinical benign presentations including cutaneous and mucosal disease, to malignant and premalignant conditions. New HPV types are currently described in the literature; many of them are characterized as high-risk types due to their oncogenic potential. Knowledge regarding their epidemiology and pathogenesis is important to understand not only infection and disease processes, but also to formulate the clinical and laboratory basis for diagnosis, therapeutics, and prophylactic measures. This non-systematic review aims to discuss and to update those aspects, with an emphasis on relevant topics for dermatologists. HPV infection and related diseases in the Brazilian scenario are highlighted, including common dermatologic conditions seen at clinics as well as the condition of a public health problem as a sexually transmitted infection. The oncogenicity of the virus and the variety of clinical outcomes - especially in the immunocompromised individuals - are addressed.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Papillomaviridae
/
Precancerous Conditions
/
Papillomavirus Infections
/
Alphapapillomavirus
Type of study:
Etiology study
/
Screening study
Limits:
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2021
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Minas Gerais State Department of Health/BR
/
Universidade Federal de Minas Gerais/BR
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