ALK+ Anaplastic large cell lymphoma with extensive cardiac involvement: A rare case report and review of the literature
Autops. Case Rep
;
11: e2020231, 2021. tab, graf
Article
in English
| LILACS
| ID: biblio-1153176
ABSTRACT
Cardiac lymphoma is a rare entity. In this setting, the secondary involvement of the heart is far more frequent than the primary cardiac lymphoma. Herein, we present an autopsy case of a disseminated anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma with a dominant mediastinal involvement. Extensive cardiac infiltration with the near replacement of the myocardial wall by the neoplastic cells was observed. A total of nine isolated case reports of anaplastic large cell lymphoma with cardiac involvement were found in the English-language literature, and a widespread cardiac and thymic infiltration by the systemic ALK-positive anaplastic large cell lymphoma has not been documented. An incidental regenerative nodule was also identified in the liver. The patient died of pulmonary thromboembolism and cardiac arrest.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Lymphoma, Large-Cell, Anaplastic
/
Heart Neoplasms
Type of study:
Prognostic study
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Autops. Case Rep
Journal subject:
Anatomia
/
Patologia Cl¡nica
/
Patologia Legal
Year:
2021
Type:
Article
Affiliation country:
India
Institution/Affiliation country:
Postgraduate Institute of Medical Education and Research/IN
/
Postgraduate Institute of Medical Education and Research,/IN
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