Asociación entre lesiones placentarias y lesiones isquémico hemorrágicas cerebrales precoces detectadas por ecografía en prematuros menores de 1500 gramos y 32 semanas / [The relationship between placental lesions and early hemorrhagic-ischemic cerebral injury in very low birth weight infants].

ABSTRACT

INTRODUCTION: The histopathological features of the placenta are central for screening a lot of pregnancy related disorders associated to hemorrhagic-ischemic cerebral injury in preterm infants that can jeopardize his long term neurodevelopment. The objective of this study was to examine the relationship between placental lesions and early hemorrhagic-ischemic cerebral injury in very low birth weight infants (VLBW). METHODS: This is a case-control study of VLBW born at Sardá Maternity Hospital, Buenos Aires, between 2006 and 2012. Inclusion criteria’s were gestational age ÔëÑ 24 and Ôëñ 32 weeks and birth weight between 500 g and 1500 g, Exclusion criteria’s were multiple pregnancy, congenital anomalies, intrauterine infections and mortality before 24 hours of life. RESULTS: 198 VLBW were included, 49 cases and 149 controls. There was no significant difference in the incidence of histopathological lesions between the groups, although inflammatory placental lesions predominated in cases (67,3