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Un inusual caso de granuloma piogeno oral multiple, ¿asociado a tratamiento con levotiroxina? / An unusual case of multiple oral pyogenic granuloma, ¿associated with treatment with levothyroxin?
Gutiérrez Patiño-Paul, Alejandro Arturo.
  • Gutiérrez Patiño-Paul, Alejandro Arturo; Hospital Nacional Edgardo Rebagliati Martins, EsSalud. Lima. PE
Rev. estomatol. Hered ; 30(4): 294-301, Oct-Dec 2020. tab, graf
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1180930
RESUMEN
RESUMEN El Granuloma piógeno (GP) es una lesión tumoral, no neoplásica, vascular, generalmente solitaria, que se presenta en la cavidad oral o piel, la etiología aún no está muy clara, se considera que es una lesión reactiva a varios estímulos de bajo grado, entre los cuales podemos contar traumas repetidos, agresiones, factores hormonales y ciertos fármacos. El GP múltiple, es un fenómeno raro, generalmente asociado al uso de drogas, como la carbamacepina, ciclosporina, retinoides, levotiroxina, etc. Se presenta el caso de una paciente de 50 años, referida por presentar aumento de volumen en reborde alveolar del primer, tercer y cuarto cuadrantes; con antecedentes de psoriasis eritrodermica e hipotiroidismo, en tratamiento con levotiroxina aproximadamente seis meses antes que se presenten las lesiones; se realiza exeresis quirúrgica y curetaje subperiostico, se enviaron las muestras a anatomía patológica, confirmándose el diagnóstico definitivo de GP; por los antecedentes, y la aparición casi simultánea de las lesiones en múltiples cuadrantes, se sospecha que estas, están asociadas al consumo terapéutico de levotiroxina para el hipotiroidismo.
ABSTRACT
SUMMARY Pyogenic Granuloma (GP) is a tumorous, non-neoplastic, vascular, generally solitary lesion that presents itself in the oral cavity or skin, the etiology is still not very clear, it is considered to be a reactive lesion to several low grade stimuli, among which we can count repeated trauma, aggressions, hormonal factors and certain drugs. The multiple GP, is a rare phenomenon, generally associated with the use of drugs, such as carbamacepine, cyclosporine, retinoids, levothyroxine, etc. It presents the case of a patient of 50 years, referred for presenting increased volume in alveolar ridge of the first, third and fourth quadrants, with a history of erythrodermic psoriasis and hypothyroidism, in treatment with levothyroxine approximately six months before the lesions occur; Surgical exeresis and subperiosteal curettage is performed, samples were sent to pathological anatomy, confirming the definitive diagnosis of GP; because of the history, and the almost simultaneous appearance of the lesions in multiple quadrants, it is suspected that these are associated with the therapeutic consumption of levothyroxine for hypothyroidism.


Full text: Available Index: LILACS (Americas) Type of study: Risk factors Language: Spanish Journal: Rev. estomatol. Hered Journal subject: Medicina Bucal / Dentistry Year: 2020 Type: Article Affiliation country: Peru Institution/Affiliation country: Hospital Nacional Edgardo Rebagliati Martins, EsSalud/PE

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Full text: Available Index: LILACS (Americas) Type of study: Risk factors Language: Spanish Journal: Rev. estomatol. Hered Journal subject: Medicina Bucal / Dentistry Year: 2020 Type: Article Affiliation country: Peru Institution/Affiliation country: Hospital Nacional Edgardo Rebagliati Martins, EsSalud/PE