Alterations in serum uric acid values in a sample of Nigerian pregnant women
Int. j. med. surg. sci. (Print)
;
6(4): 111-114, dic. 2019. tab
Article
in English
| LILACS
| ID: biblio-1247386
ABSTRACT
Introduction:
Serum uric acid level is an important prognostic variable in pregnancy as subjects with preeclampsia have elevated serum uric acid levels.Methods:
The concentrations of serum uric acid were investigated in 100 women of which 75 were pregnant women and categorized into 3 groups of 25 each, based on their trimesters of pregnancy and 25 non-pregnant women, which served as control.Results:
In the first trimester, the mean values of uric acid were 122 µmol/L with a decrease in the levels of uric acid when compared with the control levels of 308 µmol/L (p<0.05). In the second trimester, the values of uric acid were 199umol/l with a significant (p<0.05) decrease in the levels of uric acid when compared with the controls. In the third trimester of pregnancy, the values of uric acid were 360 µmol/L. There was a significant (p<0.05) increase in the level of uric acid when compared with the controls.Conclusion:
The progressive increase in the levels of uric acid through the trimesters of pregnancy suggests an impairment in uric acid excretion, may be with concomitant increase in renal tubular re-absorp-tion of uric acid, thereby leading to hyperuricaemia.
Full text:
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Index:
LILACS (Americas)
Main subject:
Uric Acid
/
Pregnancy
Type of study:
Prognostic study
Limits:
Female
/
Humans
Country/Region as subject:
Africa
Language:
English
Journal:
Int. j. med. surg. sci. (Print)
Journal subject:
Surgery
/
Medicine
Year:
2019
Type:
Article
Affiliation country:
Nigeria
Institution/Affiliation country:
University of Port Harcourt/NG
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