Case for diagnosis. Dorsal nodule in a 10-year-old male
An. bras. dermatol
;
96(2): 237-239, Mar.-Apr. 2021. graf
Article
in English
| LILACS
| ID: biblio-1248727
ABSTRACT
Abstract Granular cell tumors (GCTs) are rare soft-tissue neoplasms. GCT immunohistochemistry is positive for S-100, NSE, and CD68. This report describes the case of a 10-year-old male who presented with a dorsal nodule. A biopsy revealed aggregates and sheets of large epithelioid and spindle cells. The cells had abundant eosinophilic granular cytoplasm. Immunohistochemical analysis was positive for CD68, NKI/C3, and synaptophysin; weakly positive for NSE; and negative for S-100, SOX10, HMB45, Melan A, cytokeratin, SMA, EMA, and CD163. The Ki-67 index was less than 1%. A diagnosis of an S-100 negative, cutaneous, benign GCT was determined.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Skin Neoplasms
/
Soft Tissue Neoplasms
/
Granular Cell Tumor
Type of study:
Diagnostic study
Limits:
Child
/
Humans
/
Male
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2021
Type:
Article
Affiliation country:
China
Institution/Affiliation country:
Jinhua Fifth Hospital/CN
/
Jinhua Municipal Central Hospital/CN
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