Management of hypopituitarism: a perspective from the Brazilian Society of Endocrinology and Metabolism
Arch. endocrinol. metab. (Online)
;
65(2): 212-230, Mar.-Apr. 2021. tab, graf
Article
in English
| LILACS
| ID: biblio-1248814
ABSTRACT
ABSTRACT Hypopituitarism is a disorder characterized by insufficient secretion of one or more pituitary hormones. New etiologies of hypopituitarism have been recently described, including head trauma, cerebral hemorrhage, and drug-induced hypophysitis. The investigation of patients with these new disorders, in addition to advances in diagnosis and treatment of hypopituitarism, has increased the prevalence of this condition. Pituitary hormone deficiencies can induce significant clinical changes with consequent increased morbidity and mortality rates, while hormone replacement based on current guidelines protects these patients. In this review, we will first discuss the different etiologies of hypopituitarism and then address one by one the clinical aspects, diagnostic evaluation, and therapeutic options for deficiencies of TSH, ACTH, gonadotropin, and GH. Finally, we will detail the hormonal interactions that occur during replacement of pituitary hormones.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Endocrinology
/
Hypopituitarism
Type of study:
Practice guideline
/
Risk factors
Limits:
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Arch. endocrinol. metab. (Online)
Journal subject:
Endocrinology
/
Metabolism
Year:
2021
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
A.C. Camargo Cancer Center/BR
/
Santa Casa de Belo Horizonte/BR
/
Universidade Estadual de Campinas/BR
/
Universidade Federal de Pernambuco/BR
/
Universidade Federal de São Paulo/BR
/
Universidade Federal do Ceará/BR
/
Universidade Federal do Paraná/BR
/
Universidade Federal do Rio Grande do Sul/BR
/
Universidade Federal do Rio de Janeiro/BR
/
Universidade de Brasília/BR
Similar
MEDLINE
...
LILACS
LIS