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A case of late-onset Klebsiella oxytoca keratitis treated with topical imipenem after deep anterior lamellar keratoplasty / Caso de ceratite de início tardio por Klebsiella oxytoca tratado com imipenem tópico após ceratoplastia lamelar anterior profunda
Dursun, Özer; Dinç, Erdem; Özer, Ömer; Kiroglu, Seyma; Vatansever, Mustafa; Adigüzel, Ufuk.
  • Dursun, Özer; Mersin University. Faculty of Medicine. Department of Ophthalmology. Mersin. TR
  • Dinç, Erdem; Mersin University. Faculty of Medicine. Department of Ophthalmology. Mersin. TR
  • Özer, Ömer; Mersin University. Faculty of Medicine. Department of Ophthalmology. Mersin. TR
  • Kiroglu, Seyma; Mersin University. Faculty of Medicine. Department of Ophthalmology. Mersin. TR
  • Vatansever, Mustafa; Mersin University. Faculty of Medicine. Department of Ophthalmology. Mersin. TR
  • Adigüzel, Ufuk; Mersin University. Faculty of Medicine. Department of Ophthalmology. Mersin. TR
Arq. bras. oftalmol ; 84(3): 279-281, May-June 2021. graf
Article in English | LILACS | ID: biblio-1248970
ABSTRACT
ABSTRACT The aim of this study was to discuss a case of late-onset Klebsiella oxytoca keratitis after deep anterior lamellar keratoplasty and its treatment. A 21-year-old female patient presented with redness and effluence in the left eye at 5 months after uncomplicated deep anterior lamellar keratoplasty surgery. In the examination, a single suture was loosened in the superior nasal region and there was an infiltration area and epithelial defect in the graft and recipient bed junction in the area of the loose suture. Topical fortified vancomycin and fortified ceftazidime treatment was started empirically hourly, but there was insufficient response. After K. Oxytoca growth in a swab and suture culture taken from the patient, fortified vancomycin was replaced with fortified imipenem. It was observed that the infiltration area rapidly regressed and the epithelial defect was closed after fortified imipenem treatment. Fortified imipenem may be considered as an alternative treatment, especially in cases in which there is no response to treatment and culture growth is detected.(AU)
RESUMO
RESUMO O objetivo deste estudo é discutir um caso de ceratite tardia por Klebsiella oxytoca, após ceratoplastia lamelar anterior profunda, bem como seu tratamento. Uma paciente de 21 anos apresentou vermelhidão e efluxo no olho esquerdo 5 meses após cirurgia de ceratoplastia lamelar anterior profunda sem complicações. Ao exame, havia uma única sutura solta na região nasal superior e uma área de infiltração com defeito epitelial no enxerto e na junção com o leito receptor na área da sutura solta. Iniciou-se empiricamente um tratamento tópico com vancomicina e ceftazidima fortificada de hora em hora, porém com resposta insuficiente. Após o crescimento de K. oxytoca a partir de cultura de swab e sutura retirados da paciente, a vancomicina fortificada foi substituída por imipenem fortificado. Observou-se que a área de infiltração regrediu rapidamente e que o defeito epitelial foi fechado com o tratamento com imipenem fortificado. O imipenem fortificado pode ser considerado um tratamento alternativo, especialmente nos casos sem resposta ao tratamento e detecção de crescimento na cultura.(AU)
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Imipenem / Corneal Transplantation / Klebsiella oxytoca / Keratitis Limits: Adult / Humans / Male Language: English Journal: Arq. bras. oftalmol Journal subject: Ophthalmology Year: 2021 Type: Article Affiliation country: Turkey Institution/Affiliation country: Mersin University/TR

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Full text: Available Index: LILACS (Americas) Main subject: Imipenem / Corneal Transplantation / Klebsiella oxytoca / Keratitis Limits: Adult / Humans / Male Language: English Journal: Arq. bras. oftalmol Journal subject: Ophthalmology Year: 2021 Type: Article Affiliation country: Turkey Institution/Affiliation country: Mersin University/TR