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Optical coherence tomography angiography findings in patients with ocular and non-ocular Behcet disease / Achados de angiografia por tomografia de coerência óptica em pacientes com doença de Behçet com e sem acometimento ocular
Yilmaz, Pinar Topcu; Ozdemir, E. Yildiz; Alp, Mehmet Numan.
  • Yilmaz, Pinar Topcu; Ankara Numune Education and Research Hospital. Health Sciences University. Ankara. TR
  • Ozdemir, E. Yildiz; Ankara Numune Education and Research Hospital. Health Sciences University. Ankara. TR
  • Alp, Mehmet Numan; Ankara Numune Education and Research Hospital. Health Sciences University. Ankara. TR
Arq. bras. oftalmol ; 84(3): 235-240, May-June 2021. tab
Article in English | LILACS | ID: biblio-1248975
ABSTRACT
ABSTRACT

Purposes:

To evaluate the optical coherence tomography angiography findings in patients with Behçet disease with and without ocular involvement.

Methods:

A total of 40 patients with Behçet disease and 30 healthy controls were enrolled in the study. Retinal vessel density in the superficial capillary plexus and deep capillary plexus, foveal avascular zone area and perimeter, acirculatory index, foveal density, and nonflow area in the superficial retina were automatically measured using the optical coherence tomography angiography software AngioVue and compared between the groups.

Results:

The mean parafoveal and perifoveal vessel densities in the superficial capillary plexus and deep capillary plexus and foveal density were significantly lower in the eyes with Behçet uveitis compared to the eyes without Behçet uveitis and eyes of the healthy controls. In the eyes with Behçet uveitis, logMAR visual acuity showed a moderate correlation with parafoveal and perifoveal vessel densities and foveal density (r=-0.43, p=0.006; r=-0.62, p<0.001; r=-0.42, p=0.008; respectively).

Conclusion:

Behçet disease with posterior uveitis was associated with significant perifoveal and parafoveal vascular decrements in the superficial and deep retina.(AU)
RESUMO
RESUMO

Objetivo:

Avaliar achados de angiografia por tomografia de coerência óptica em pacientes com doença de Behçet com e sem acometimento ocular.

Métodos:

Foram incluídos 40 pacientes com doença de Behçet e 30 controles saudáveis. A densidade vascular retiniana nos plexos capilares superficial e profundo, a zona avascular foveal, o índice de circularidade, a densidade foveal e a área sem fluxo da retina superficial foram medidos automaticamente, através do software AngioVue para angiografia por tomografia de coerência óptica, e comparados entre os grupos.

Resultados:

A densidade vascular parafoveal e perifoveal média nos plexos capilares superficial e profundo, bem como a densidade foveal, foram significativamente menores nos olhos com uveíte de Behçet em comparação com os olhos sem uveíte de Behçet e os olhos dos controles saudáveis. Nos olhos com uveíte de Behçet, a acuidade visual logMAR mostrou correlação moderada com a densidade vascular parafoveal e perifoveal e com a densidade foveal (respectivamente, r=-0,43, p=0,006; r=-0,62, p<0,001; e r=-0,42, p = 0,008).

Conclusão:

A doença de Behçet com uveíte posterior foi associada a decréscimos significativos da vascularização perifoveal e parafoveal na retina superficial e profunda.(AU)
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Uveitis / Angiography / Behcet Syndrome / Tomography, Optical Coherence / Fovea Centralis Type of study: Diagnostic study Limits: Humans Language: English Journal: Arq. bras. oftalmol Journal subject: Ophthalmology Year: 2021 Type: Article Affiliation country: Turkey Institution/Affiliation country: Ankara Numune Education and Research Hospital/TR

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Full text: Available Index: LILACS (Americas) Main subject: Uveitis / Angiography / Behcet Syndrome / Tomography, Optical Coherence / Fovea Centralis Type of study: Diagnostic study Limits: Humans Language: English Journal: Arq. bras. oftalmol Journal subject: Ophthalmology Year: 2021 Type: Article Affiliation country: Turkey Institution/Affiliation country: Ankara Numune Education and Research Hospital/TR