Your browser doesn't support javascript.
loading
An unusual case of adamantinoma of long bone
Kumar, Arvind; Sharma, Ruchi; Verma, Anil Kumar; Tiwari, Abhijeet; Mishra, Jyoti.
  • Kumar, Arvind; All India Institute of Medical Sciences. Department of Pathology and Laboratory Medicine. Rishikesh. IN
  • Sharma, Ruchi; All India Institute of Medical Sciences. Department of Transfusion Medicine & Blood Bank. Raipur. IN
  • Verma, Anil Kumar; All India Institute of Medical Sciences. Department of Transfusion Medicine & Blood Bank. Raipur. IN
  • Tiwari, Abhijeet; NH MMI Narayana Superspeciality Hospital. Raipur. IN
  • Mishra, Jyoti; School of Medical Sciences and Research. Sharda Hospital. Department of Pathology. Greater Noida. IN
Autops. Case Rep ; 11: e2021276, 2021. tab, graf
Article in English | LILACS | ID: biblio-1249019
ABSTRACT
Adamantinoma of the long bones is an exceedingly rare and slow-growing tumor that affects the diaphysis of long bones, particularly the tibia. Based on the pattern of the epithelial cell component and the presence or absence of the osteofibrous dysplasia-like element, several histological variants have been described, such as (i) tubular (the most frequent), (ii) basaloid, (iii) squamous, (iv) spindle variant, (v) osteofibrous dysplasia -like variant, and (vi) Ewing's sarcoma - like adamantinoma (the least frequent). The diagnosis may be challenging since this tumor may be mistakenly interpreted as carcinoma, myoepithelial tumor, osteofibrous dysplasia, and vascular tumor. We report the case of a 41-year-old male who presented with swelling over the right leg associated with pain. The X-ray showed a lytic lesion of the right-sided tibia. The diagnosis of adamantinoma was made based on the clinico-radiological, histomorphology, and immunohistochemical findings. Histologically, classic adamantinoma is a biphasic tumor characterized by epithelial and osteofibrous components in varying proportions and differentiating patterns. The diagnosis can be confirmed by immunohistochemistry for demonstrating sparse epithelial cell nests when the radiological features are strongly consistent with adamantinoma. This case is highlighted because the epithelial component can lead to a misdiagnosis, particularly when the clinico-radiological features are overlooked. Adamantinoma of long bones has the potential for local recurrence and may metastasize to the lungs, lymph nodes, or other bones. The prognosis is good if early intervention is taken.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Tibia / Adamantinoma Type of study: Prognostic study Limits: Adult / Humans / Male Language: English Journal: Autops. Case Rep Journal subject: Anatomia / Patologia Cl¡nica / Patologia Legal Year: 2021 Type: Article Affiliation country: India Institution/Affiliation country: All India Institute of Medical Sciences/IN / NH MMI Narayana Superspeciality Hospital/IN / School of Medical Sciences and Research/IN

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: Tibia / Adamantinoma Type of study: Prognostic study Limits: Adult / Humans / Male Language: English Journal: Autops. Case Rep Journal subject: Anatomia / Patologia Cl¡nica / Patologia Legal Year: 2021 Type: Article Affiliation country: India Institution/Affiliation country: All India Institute of Medical Sciences/IN / NH MMI Narayana Superspeciality Hospital/IN / School of Medical Sciences and Research/IN