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Enfermedad de Crohn con compromiso extenso y manifestaciones extradigestivas inusuales: a propósito de un caso / Crohn's disease with extensive involvement and rare extraintestinal manifestations: A case report
Mosquera-Klinger, Gabriel; Yepes-Madrid, Nathalie; Carvajal-Gutiérrez, Jhon Jaime.
  • Mosquera-Klinger, Gabriel; Hospital Pablo Tobón Uribe. Medellín. CO
  • Yepes-Madrid, Nathalie; Pontificia Universidad Javeriana. Cali. CO
  • Carvajal-Gutiérrez, Jhon Jaime; Hospital Pablo Tobón Uribe. Medellín. CO
Rev. colomb. gastroenterol ; 36(supl.1): 85-90, abr. 2021. tab, graf
Article in Spanish | LILACS | ID: biblio-1251553
Responsible library: CO354
RESUMEN
Resumen La enfermedad de Crohn (EC) es considerada una entidad inmunológicamente mediada que compromete el tracto digestivo. Su compromiso suele ser transmural y puede afectar cualquier parte del tubo digestivo, desde la cavidad oral hasta el ano. Aunque se sabe que su extensión es variable, es poco habitual ver un compromiso extenso y multiorgánico. Se presenta el caso de un paciente joven, quien debutó con síntomas pulmonares asociados con la EC y años más tarde se presentaron los síntomas digestivos y de la vía biliar. El tratamiento se basó en la terapia con anticuerpos contra el factor de necrosis tumoral alfa (TNF-α), con lo cual se obtuvo una respuesta clínica satisfactoria. La relevancia clínica de este caso es la forma de presentación clínica tan florida, tanto por el compromiso gastrointestinal extenso como por las manifestaciones extradigestivas tan infrecuentes.
ABSTRACT
Abstract Crohn's disease (CD) is considered an immunologically mediated entity that involves the digestive tract. It is characterized by transmural inflammation and can affect any part of the digestive tract, from the oral cavity to the anus. Although it is recognized that its severity varies, extensive and multiple organ failure is unusual. We present the case of a young patient, who initially presented with pulmonary symptoms associated with CD. Years later, digestive and bile duct symptoms appeared. Treatment was based on anti-tumor necrosis factor-alpha antibody therapy, resulting in a satisfactory clinical response. The clinical relevance of this case is its full-blown presentation, which includes extensive gastrointestinal involvement and rare extraintestinal manifestations.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Crohn Disease Type of study: Case report Limits: Adult / Humans / Male Language: Spanish Journal: Rev. colomb. gastroenterol Journal subject: Gastroenterology Year: 2021 Type: Article Affiliation country: Colombia Institution/Affiliation country: Hospital Pablo Tobón Uribe/CO / Pontificia Universidad Javeriana/CO

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Full text: Available Index: LILACS (Americas) Main subject: Crohn Disease Type of study: Case report Limits: Adult / Humans / Male Language: Spanish Journal: Rev. colomb. gastroenterol Journal subject: Gastroenterology Year: 2021 Type: Article Affiliation country: Colombia Institution/Affiliation country: Hospital Pablo Tobón Uribe/CO / Pontificia Universidad Javeriana/CO