Transcriptome profiling reveals differential expression of genes potentially involved in muscle and adipose tissue development of cattle
Electron. j. biotechnol
;
48: 72-77, nov. 2020. tab, ilus
Article
in English
| LILACS
| ID: biblio-1254810
ABSTRACT
BACKGROUND:
To identify differentially expressed genes (DEGs) between muscle and adipose in cattle, we analyzed the data from the RNA sequencing of three Angus×Qinchuan crossbred cattle.RESULTS:
Searched the Gene Expression Omnibus (GEO) for a microarray dataset of Yan yellow cattle, GSE49992. After the DEGs were identified, we used STRING and Cytoscape to construct a proteinprotein interaction (PPI) network, subsequently analyzing the major modules of key genes. In total, 340 DEGs were discovered, including 21 hub genes, which were mainly enriched in muscle contraction, skeletal muscle contraction, troponin complex, lipid particle, Z disc, tropomyosin binding, and actin filament binding.CONCLUSIONS:
In summary, these genes can be regarded as candidate biomarkers for the regulation of muscle and adipose development.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Adipose Tissue
/
Muscle Development
/
Transcriptome
Limits:
Animals
Language:
English
Journal:
Electron. j. biotechnol
Journal subject:
Biotechnology
Year:
2020
Type:
Article
Affiliation country:
China
/
New Zealand
/
United States
Institution/Affiliation country:
Massey University/NZ
/
Northwest A&F University/CN
/
Utah State University/US
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