Investigation of an outbreak of acute respiratory disease in Côte d'Ivoire in april 2007
Afr. j. infect. dis. (Online)
;
8(2): 31-35, 2014. ilus
Article
in English
| AIM
| ID: biblio-1257277
ABSTRACT
Background:
This study aim was to investigate an outbreak of human cases of unexplained influenza-like illness and fatal acute respiratory infection (ARI); with simultaneous poultry illness and high mortality raising concerns of possible influenza A (H5N1); virus in Cote d'Ivoire in February and March 2007. Materials andMethods:
To investigate the outbreak; we conducted active surveillance in the community and reviewed health registries. Persons meeting the case definition were asked to provide nasopharyngeal specimens. On the basis of clinical and epidemiological information; specimens were tested using conventional RT-PCR for the M gene of the influenza viruses and hemagglutinin H5 of avian influenza A (H5N1); virus; negative samples were tested for other respiratory viruses. Specimens from healthy animals were also collected.Results:
Between October 2006; and February 2007; 104 suspected cases of Acute Respiratory Disease that included; 31 deaths recorded. We collected and tested 73 nasopharyngeal specimens; of which; 2; were positive for human Coronavirus OC43 and 1 for influenza C virus. No pathogens were identified in animal specimens.Conclusions:
The investigation quickly ruled out influenza A (H5N1); virus as the cause and found laboratory-confirmed cases of influenza C virus and human Coronavirus OC 43 for the first time in both Cote d'Ivoire and in a Sub-Saharan African country. However we were not able to show that these viruses caused the outbreak. Monitoring of influenza viruses must be a priority but other respiratory viruses and non-viral causes may be of interest too
Full text:
Available
Index:
AIM (Africa)
Main subject:
Disease Outbreaks
/
Cote d'Ivoire
/
Severe Acute Respiratory Syndrome
/
Influenza, Human
/
Public Health Surveillance
Country/Region as subject:
Africa
Language:
English
Journal:
Afr. j. infect. dis. (Online)
Year:
2014
Type:
Article
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