Effects of cucumis metuliferus e mey. Ex naud (cucurbitaceae) fruit extract on some male reproductive parameters in adult rats
Afr. j. pharm. pharmacol
;
2(3): 48-51, 2008. ilus
Article
in English
| AIM
| ID: biblio-1257553
ABSTRACT
The effect of the extract of Cucumis metuliferus fruit on some male reproductive parameters was investigated in albino rats. The LD50 of the extract was above 5000 mg/kg body weight when administered orally. Histological studies showed that there was no remarkable change in the testes histology compare to the control. The effects on sperm cells showed a statistically significant (P0.05) increase in total sperm count with an insignificant (P0.05) increase in viability count in rats treated with 500 mg/kg dose point. On the other hand; 1000 mg/kg dose point produced significant (P0.05) decrease in total sperm count and viability count compare to control. This result suggests that C. metuliferus fruit extracts could be beneficial in increasing sperm/semen integrity
Full text:
Available
Index:
AIM (Africa)
Main subject:
Reproduction
/
Sperm Count
/
Cucumis
/
Animal Experimentation
/
Nigeria
Country/Region as subject:
Africa
Language:
English
Journal:
Afr. j. pharm. pharmacol
Year:
2008
Type:
Article
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