Plasma Concentration of Ascorbic Acid and Some Hematological Parameters in Tobacco Snuffers Among the Igbos of Southeastern Nigeria
Ann. med. health sci. res. (Online)
;
2(1): 46-48, 2012.
Article
in English
| AIM
| ID: biblio-1259222
RESUMO
Tobacco snuffing; like cigarette smoking; is known to be a common habit among the adults of Igbo communities in Nigeria. In view of the various pharmacological actions of nicotine and other additive constituents of tobacco snuff; there is growing concern that ascorbic acid; which is a vital antioxidant; and blood cell production or morphology may be affected. Objective:
To investigate the possible effects of prolonged use of tobacco snuff on plasma ascorbic acid concentrations and some hematological parameters. Materials andMethods:
Fifty adults of Igbo extraction (35 males and 15 females) residents in and around Enugu metropolis; who have been snuffing tobacco for 6 years and above; were recruited for the study; after they gave informed consent. Also; 50 apparently healthy; age-matched persons (25 males; 25 females); who do not smoke or take tobacco snuff; served as controls. Spectrophotometric method was adopted for ascorbic acid determination while hematological profiles were assessed by Bain method.Results:
The results showed no significant difference in the measured parameters relative to the controls AA (P=0.08); Hb (P=0.19); PCV (P=0.10); RC (P=0.06); PC (P=0.20); WBC (P=0.09).Conclusion:
The results of the study suggest that tobacco snuff inhalation may not adversely affect plasma ascorbic acid concentration and hematological parameters in adult humans. The study; however; has not concluded that tobacco snuffing is totally wholesome
Full text:
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Index:
AIM (Africa)
Main subject:
Plant Poisoning
/
Rural Population
/
Nicotiana
/
Acids
/
Mouth Neoplasms
/
Lakes
/
Oxidative Stress
/
Pharmacologic Actions
/
Lobeline
/
Nigeria
Country/Region as subject:
Africa
Language:
English
Journal:
Ann. med. health sci. res. (Online)
Year:
2012
Type:
Article
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